[Effect of increased functional activity of skeletal muscles on the turnover rate of heavy and light chains in myosin].

Incorporation of 14C-leucine into light chains (LC) of myosin was distinctly increased and into heavy chains (HC)--decreased during physical exercises. Within first six hours after the exercises synthesis of HC maintained at the reduced level, then it was gradually elevated and distinctly activated after 48 hrs rest. Incorporation of 14C-leucine into LC of myosin was unaltered at the post-exercise period. During swimming turnover of LC myosin was accelerated and after physical activity it maintained at the level of controls. The rate of HC myosin turnover was not distinctly altered both during physical activity and within the first day after the loading. The rate of HC myosin turnover was augmented within 48 hrs after exercises.