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[数字支持的风湿病筛查咨询:问卷评分系统(RhePort)有多有用?]

[Digitally supported rheumatological screening consultation : How useful is a questionnaire scoring system (RhePort)?].

作者信息

Engel Andreas, Brandl Julia, Gao Ino K, Jacki Swen, Meier Maria-Anna, Weidner Sven, Henes Jörg

机构信息

Rheumatologische Schwerpunktpraxis, Rotebühlstr. 66, 70178, Stuttgart, Deutschland.

Medizinische Universitätsklinik Abt. II, Tübingen, Deutschland.

出版信息

Z Rheumatol. 2022 Oct;81(8):699-704. doi: 10.1007/s00393-022-01230-4. Epub 2022 Jun 30.

Abstract

Regarding scarce capacities an early detection consultation (EDC) was established to discriminate patients in an outpatient setting with inflammatory from non-inflammatory rheumatic diseases. A total of 500 patients suspected of having a rheumatic disease received an appointment within 2 weeks. They were interviewed with the help of a digital questionnaire (RhePort), briefly physically examined followed by a determination of CRP. The questionnaire answers were scored using an algorithm within RhePort (from 0 = non-inflammatory to 4 = highly probably inflammatory). Likewise, after completion of the EDC, the rheumatologists scored the overall assessment. The RhePort score and EDC score were compared with the "true" diagnosis made in a detailed second examination after an average of 10 weeks. In 490 evaluable patients 133 inflammatory (27%) and 357 noninflammatory rheumatic diseases (73%) were diagnosed. A classification based solely on the RhePort questionnaire (score > 1) identified 103 out of 129 as inflammatory (sens. 80%) and 125 out of 355 as non-inflammatory (spec. 35%) resulting in an AUC of 0.62 after ROC analysis. With a score > 1, the rheumatological assessment after EDC classified 130 out of 133 patients as inflammatory (sensitivity 98%) and 261 out of 357 as non-inflammatory (specificity 73%). The combined EDC can decisively increase the sensitivity and specificity compared to an "automated" survey by means of a digital questionnaire alone. In addition to the early identification and treatment of inflammatory patients, rapid identification of patients who are not in need of rheumatological treatment can create capacities for care.

摘要

针对医疗资源稀缺的情况,设立了早期诊断咨询(EDC),以便在门诊环境中区分患有炎性风湿性疾病和非炎性风湿性疾病的患者。共有500名疑似患有风湿性疾病的患者在2周内获得了预约。借助数字问卷(RhePort)对他们进行了访谈,随后进行了简要的体格检查,接着测定了CRP。问卷答案通过RhePort中的算法进行评分(从0 =非炎性到4 =极有可能是炎性)。同样,在完成EDC后,风湿病专家对总体评估进行评分。将RhePort评分和EDC评分与平均10周后进行的详细二次检查得出的“真实”诊断进行比较。在490名可评估患者中,诊断出133例炎性风湿性疾病(27%)和357例非炎性风湿性疾病(73%)。仅基于RhePort问卷(评分>1)的分类在129例炎性疾病中识别出103例(敏感性80%),在355例非炎性疾病中识别出125例(特异性35%),经ROC分析后AUC为0.62。评分>1时,EDC后的风湿病学评估将133例患者中的130例分类为炎性(敏感性98%),357例中的261例分类为非炎性(特异性73%)。与仅通过数字问卷进行的“自动化”调查相比,联合EDC可显著提高敏感性和特异性。除了早期识别和治疗炎性患者外,快速识别不需要风湿病治疗的患者可为医疗护理腾出资源。

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