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原发性心脏血管肉瘤一例的手术及多学科治疗方法:病例报告

Surgical and multitreatment approach in a case of primary cardiac angiosarcoma: A case report.

作者信息

Kobayashi Akihiro, Araki Yoshimori, Terada Takafumi, Terazawa Sachie, Kawaguchi Osamu

机构信息

Department of Cardiac Surgery, Toyota Kosei Hospital, Ibobara 500-1, Jousui-cho, Toyota, Aichi 470-0396, Japan.

Department of Cardiac Surgery, Toyota Kosei Hospital, Ibobara 500-1, Jousui-cho, Toyota, Aichi 470-0396, Japan.

出版信息

Int J Surg Case Rep. 2022 Jul;96:107349. doi: 10.1016/j.ijscr.2022.107349. Epub 2022 Jun 24.

Abstract

INTRODUCTION AND IMPORTANCE

Primary cardiac angiosarcoma is extremely rare, and its prognosis remains poor, with a mean life expectancy of only a few months. Here, we report a case of primary cardiac angiosarcoma.

CASE PRESENTATION

A 49-year-old Japanese woman with a month-long history of dyspnea was admitted to our hospital for pericardial effusion. Chest computed tomography and cardiac magnetic resonance imaging showed a mass in the right atrium. The patient underwent surgical resection of the tumor, and the pathological diagnosis was angiosarcoma. The patient received radiotherapy after surgery. Six months following surgery, she underwent chemotherapy following the diagnosis of lung metastasis. The patient died 18 months after the initial diagnosis.

CLINICAL DISCUSSION

Cardiac angiosarcoma is rare and difficult to diagnose early because it is associated with few symptoms. Moreover, there are currently no established guidelines for the treatment of this disease because of its rarity and sparse descriptive literature Therefore, multidisciplinary therapies should be considered, including surgery, radiotherapy, and chemotherapy.

CONCLUSION

There is no standard treatment for cardiac angiosarcoma, but surgical resection, chemotherapy, radiation therapy, or a combination of these therapies may be useful.

摘要

引言与重要性

原发性心脏血管肉瘤极为罕见,其预后仍然很差,平均预期寿命仅几个月。在此,我们报告一例原发性心脏血管肉瘤病例。

病例介绍

一名有长达一个月呼吸困难病史的49岁日本女性因心包积液入住我院。胸部计算机断层扫描和心脏磁共振成像显示右心房有一个肿块。患者接受了肿瘤手术切除,病理诊断为血管肉瘤。患者术后接受了放疗。术后六个月,在诊断出肺转移后接受了化疗。患者在初次诊断后18个月死亡。

临床讨论

心脏血管肉瘤罕见且早期难以诊断,因为其症状较少。此外,由于该病罕见且描述性文献稀少,目前尚无既定的治疗指南。因此,应考虑多学科治疗,包括手术、放疗和化疗。

结论

心脏血管肉瘤没有标准治疗方法,但手术切除、化疗、放疗或这些疗法的联合应用可能有效。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e0c0/9284058/72b7819d502e/gr1.jpg

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