Alvarado Hospital, San Diego, CA, USA.
David Geffen School of Medicine at UCLA, Los Angeles, CA, USA.
Sex Med Rev. 2022 Jul;10(3):409-420. doi: 10.1016/j.sxmr.2021.12.005.
Across many cultures, penis size has been associated with virility, and concerns about penile length are commonplace. Peyronie's disease (PD) is a known acquired cause of penile shortening.
This paper describes the psychosocial impacts of penile length on men and their partners, both generally and in men with PD, and evaluates the effect of PD treatments (eg, collagenase clostridium histolyticum , surgery, mechanical therapy) on this outcome measure.
A PubMed database search was performed for English language articles through July 2021. Main outcome measures were association of penile length with emotional well-being, selfesteem, and relationship satisfaction in men with PD, and change from baseline penile length after treatment.
Shortened penile length caused by PD can negatively impact patient and partner quality of life, including effects on body image, emotional well-being, sexual function, and interpersonal relationships. In men with PD, studies have demonstrated an association between loss of penile length and emotional problems, reduced satisfaction with sexual performance, poor self-esteem, depression, and relationship difficulties. Loss of penile length can frequently occur after surgery for PD (including plication, plaque incision/excision with grafting, and penile implant). Advanced surgical techniques may preserve/increase penile length, but the increased risks associated with these complex procedures must be carefully considered. Treatment with collagenase clostridium histolyticum does not appear to negatively impact penile length, and 5-year follow-up data suggest potential longterm posttreatment improvements in this outcome measure. Penile traction therapy, either alone or as adjunctive therapy, may increase penile length in men with PD, but nonadherence may limit improvement.
Changes in penile length are important to many men, particularly those with PD, and should be considered during PD treatment selection. Penile length should be measured objectively before and after treatment for PD and should be included as an outcome measure in future studies on treatment effectiveness. Goldstein I, Gelbard MK, Lipshultz LI. Clinical Significance of Shortened Penile Length and Alterations in Penile Length Following Treatment for Peyronie's Disease. Sex Med Rev 2022;10:409-420.
在许多文化中，阴茎大小与男子气概有关，对阴茎长度的担忧很常见。佩罗尼氏病（PD）是已知的导致阴茎缩短的后天原因。
本文描述了阴茎长度对男性及其伴侣的心理社会影响，包括 PD 男性的普遍影响和影响，以及评估 PD 治疗（例如，胶原酶组织溶菌素、手术、机械治疗）对该结果测量的影响。
通过 2021 年 7 月对 PubMed 数据库进行了英文文献检索。主要结果测量指标是 PD 患者中阴茎长度与情绪健康、自尊和关系满意度的关系，以及治疗后从基线阴茎长度的变化。
PD 引起的阴茎缩短会对患者和伴侣的生活质量产生负面影响，包括对身体形象、情绪健康、性功能和人际关系的影响。在 PD 男性中，研究表明阴茎长度丧失与情绪问题、性表现满意度降低、自尊心降低、抑郁和关系困难有关。PD 手术后常发生阴茎长度丧失（包括折叠术、斑块切开/切除加移植术和阴茎植入术）。先进的手术技术可能会保留/增加阴茎长度，但必须仔细考虑这些复杂手术带来的风险增加。胶原酶组织溶菌素治疗似乎不会对阴茎长度产生负面影响，5 年随访数据表明该结果测量的潜在长期治疗后改善。阴茎牵引治疗，单独或作为辅助治疗，可增加 PD 男性的阴茎长度，但不坚持可能会限制改善。
阴茎长度的变化对许多男性，特别是 PD 男性很重要，在 PD 治疗选择时应考虑。在 PD 治疗前后应客观测量阴茎长度，并将其作为未来治疗效果研究的结果测量指标之一。
