Department of Neurology, Massachusetts General Hospital, Boston, MA, United States.
Division of Neuroanesthesia and Intraoperative Neuromonitoring, Department of Anesthesia, Intensive Care and Pain Therapy, Klinikum St. Georg, Hospital of the University of Leipzig, Leipzig, Germany.
Handb Clin Neurol. 2022;186:355-374. doi: 10.1016/B978-0-12-819826-1.00015-6.
Cerebral ischemia during carotid endarterectomy occurs via several mechanisms: inadequate collateral blood flow during carotid cross-clamping, thromboembolism due to carotid manipulation, and/or rethrombosis at the surgical site. Perioperative strokes increase not only the morbidity of endarterectomy but also its short- and long-term mortality. However, while several predictors of cerebral ischemia have been identified, precise individual risk is hard to assess. Since nonselective shunting during carotid cross-clamping is neither risk-free nor eliminates perioperative stroke, it is advisable to apply intraoperative monitoring techniques for detection and reversal of cerebral ischemia, which may occur at various stages of the procedure. This chapter addresses the methods available for monitoring, with an emphasis on neurophysiologic techniques, which are preferable given their direct assessment of how a decrease in cerebral blood flow impacts brain function. These include electroencephalography, somatosensory evoked potentials, and transcranial motor evoked potentials. Details regarding the methodology, advantages, disadvantages, and interpretation of these tests will be discussed within the anatomic, physiologic, surgical, and anesthetic contexts.
颈动脉夹闭期间的侧支循环血流不足、颈动脉操作引起的血栓栓塞,以及/或手术部位的再血栓形成。围手术期中风不仅增加了内膜切除术的发病率,而且还增加了其短期和长期死亡率。然而,尽管已经确定了几个脑缺血的预测因素,但很难准确评估个体风险。由于颈动脉夹闭期间的非选择性分流既不安全,也不能消除围手术期中风,因此建议应用术中监测技术来检测和逆转可能在手术过程的不同阶段发生的脑缺血。本章介绍了现有的监测方法,重点介绍了神经生理技术,由于它们直接评估脑血流减少对脑功能的影响,因此是首选方法。这些方法包括脑电图、体感诱发电位和经颅运动诱发电位。将在解剖、生理、手术和麻醉背景下讨论这些测试的方法、优点、缺点和解释的详细信息。