Wiessmann K J, Dalhoff K, Schultek T, Mansky T
Z Gerontol. 1987 Jan-Feb;20(1):17-22.
Chronic obstructive lung disease (COLD), especially obstructive bronchitis and obstructive lung emphysema, are the most common pulmonary diseases of the elderly. In around 10% of over 65's they cause the death of the individual. The aetiology of these phenomena is still not clear. In pathophysiological terms, a loss in lung function occurs during the natural process of aging, pulmonary and extrapulmonary disease and other environmental factors. Any reduction in function of other organ systems must be taken into consideration when ordering therapeutical measures in treating COLD. The following stepwise-orientated scheme can be recommended in the treatment of COLD in elderly patients: Theophylline, beta 2-adrenergic agents, Anticholinergic drugs, Corticoid therapy, Mucolytica and secretolytica, Physiotherapy, Measures to increase arterial pO2 - either with oxygen therapy at home or with Almitrin, Antibiotica.
慢性阻塞性肺疾病(COLD),尤其是阻塞性支气管炎和阻塞性肺气肿,是老年人最常见的肺部疾病。在65岁以上的人群中,约10%的人因此病死亡。这些现象的病因仍不清楚。从病理生理学角度来看,在自然衰老过程、肺部和肺外疾病以及其他环境因素作用下,肺功能会出现下降。在为慢性阻塞性肺疾病患者制定治疗措施时,必须考虑其他器官系统功能的任何减退。对于老年慢性阻塞性肺疾病患者的治疗,可推荐以下逐步导向方案:茶碱、β2肾上腺素能药物、抗胆碱能药物、皮质类固醇疗法、黏液溶解剂和促分泌剂、物理治疗、提高动脉血氧分压的措施——在家进行氧疗或使用阿米三嗪、抗生素。