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[老年呼吸医学。治疗问题]

[Respiratory medicine in the aged. Therapeutic problemsd].

作者信息

Leonardi R, Cossi S, De Martinis M, Ghisla M K, Tomasi M F, Grassi V

机构信息

Cattedra di Medicina Interna I, Università di Brescia, I Divisione di Medicina, Azienda Ospedaliera Spedali Civili, Brescia.

出版信息

Recenti Prog Med. 1997 Dec;88(12):566-73.

PMID:9522597
Abstract

Chronic obstructive pulmonary disease (COPD) is very common in the elderly, and its treatment needs special concern. Data from two clinical studies (in-patients of an Internal Medicine Department and Nursing-Home, respectively) have been evaluated in order to compare therapeutic approaches to COPD in three separate settings: home, hospital and Nursing-Home. Less than 50% of the overall patients received medical treatment according to the guidelines emerged in the literature. Although cardiovascular problems were highly common in out-patients, their bronchodilator therapy included systemic beta 2-agonists. Theophylline was the main drug prescribed to in-patients discharged from hospital, although inhaling beta 2-agonists were also recommended in few cases. Topical steroids have been widely used. Nursing-Home patients received mostly systemic steroids and few of them had theophylline and inhaling steroids. Anti-cholinergic drugs have never been employed in the overall population of elderly patients. Data concerning medical treatment of infectious respiratory diseases of Nursing-Home patients (both with and without COPD) have also been evaluated. Antimicrobial therapy has been performed according to the special needs of the elderly. During COPD reacutizations, beta 2-agonists and, again, theophylline consumption increased.

摘要

慢性阻塞性肺疾病(COPD)在老年人中非常常见,其治疗需要特别关注。为了比较在家庭、医院和疗养院三种不同环境下对COPD的治疗方法,对两项临床研究(分别来自内科住院患者和疗养院)的数据进行了评估。总体患者中不到50%根据文献中出现的指南接受药物治疗。虽然心血管问题在门诊患者中非常常见,但他们的支气管扩张剂治疗包括全身性β2激动剂。茶碱是出院住院患者的主要处方药,尽管少数情况下也推荐吸入β2激动剂。局部用类固醇已被广泛使用。疗养院患者大多接受全身性类固醇治疗,很少有人使用茶碱和吸入性类固醇。抗胆碱能药物从未在老年患者总体中使用过。还评估了有关疗养院患者(无论是否患有COPD)感染性呼吸道疾病药物治疗的数据。抗菌治疗已根据老年人的特殊需求进行。在COPD急性加重期间,β2激动剂以及茶碱的消耗量增加。

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