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经口入路颈椎手术后手术部位感染的发生率及处理。

Incidence and management of surgical site infection in the cervical spine following a transoral approach.

机构信息

The First School of Clinical Medicine, Southern Medical University, Guangzhou, Guangdong, China.

Department of Orthopedic, People's Liberation Army General Hospital of Southern Theatre Command, Guangzhou, Guangdong, China.

出版信息

Int Orthop. 2022 Oct;46(10):2329-2337. doi: 10.1007/s00264-022-05492-0. Epub 2022 Jun 30.

Abstract

PURPOSE

Transoral approach can accomplish ventral decompression directly. However, surgical site infection (SSI) cannot be ignored. This paper aims to review the prevalence of infection and conduct advice for the treatment of SSI in the cervical spine following the transoral approach.

METHODS

A retrospective analysis of patients with SSI after transoral atlantoaxial reduction plate (TARP) surgery was performed. SSI was classified into three kinds according to the modified American CDC criteria.

RESULTS

2.9% (17/581) patients who underwent TARP surgery, experienced SSI, of which five had superficial SSI (SI), eight had deep SSI (DI), and four had organ/space SSI (O/SI). The patients with SI underwent intravenous antibiotic treatment and were ultimately cured. Among the remaining 12 patients with DI and O/SI, 11 underwent reoperation for TARP system removal and subsequently one-stage posterior occipitocervical fixation, and one patient experienced infection two months post-operatively and died without receiving treatment. Among patients who underwent revision surgery, three experienced intracranial infection due to intra-operative dural tears, and continuous lumbar cerebrospinal fluid drainage and intrathecal injection of antibiotics were used as effective and appropriate treatments, with outcomes of one recovery and two deaths. All patients with SSI were begun on intravenous antibiotics with conversion to oral antibiotics.

CONCLUSIONS

The incidence of SSI was 2.9% (17/581). Adequate peri-operative preparation, early diagnosis, and appropriate treatment of SSI require further research.

摘要

目的

经口入路可直接完成腹侧减压,但不能忽视手术部位感染(SSI)。本文旨在回顾经口颈椎前路寰枢复位板(TARP)术后感染的发生率,并为颈椎前路 TARP 术后 SSI 的治疗提供建议。

方法

对经口寰枢复位板(TARP)手术后发生 SSI 的患者进行回顾性分析。根据改良的美国 CDC 标准,将 SSI 分为三种类型。

结果

581 例行 TARP 手术的患者中,2.9%(17/581)发生 SSI,其中 5 例为浅表性 SSI(SI),8 例为深部 SSI(DI),4 例为器官/间隙 SSI(O/SI)。SI 患者接受静脉抗生素治疗,最终治愈。在其余 12 例 DI 和 O/SI 患者中,11 例因 TARP 系统取出和随后一期后路枕颈固定而行再次手术,1 例患者术后 2 个月发生感染,未接受治疗而死亡。在接受 revision surgery 的患者中,3 例因术中硬脑膜撕裂而发生颅内感染,采用持续腰椎脑脊液引流和鞘内注射抗生素作为有效且合适的治疗方法,结果 1 例恢复,2 例死亡。所有 SSI 患者均开始静脉应用抗生素,并转为口服抗生素。

结论

SSI 的发生率为 2.9%(17/581)。需要进一步研究充分的围手术期准备、早期诊断和 SSI 的适当治疗。

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