Xu Ping, Wang Jianzhang, Zhang Yanan, Zhu Libo, Zhang Xinmei
Department of General Gynecology, Women's Hospital School of Medicine Zhejiang University, Hangzhou, China.
Front Surg. 2022 Jun 14;9:914661. doi: 10.3389/fsurg.2022.914661. eCollection 2022.
This study aims to evaluate the factors associated with complications and long-term results in the surgical treatment of intestinal deep endometriosis and to figure out the optimized treatment measures for bowel endometriosis.
A retrospective study was performed in a single center in China. Medical charts were reviewed from 61 women undergoing surgical treatment for bowel endometriosis between January 2013 and August 2019 in the Department of General Gynecology, Women's Hospital School of Medicine Zhejiang University. Multivariate regression analysis was utilized to investigate the impact of the stages of endometriosis and surgical steps (independent risk factors) on complications (and postoperative bowel dysfunction). The clinical characters, surgical procedures, postoperative treatment, complications, and recurrence rate were summarized and analyzed by using Lasso regression.
Surgery type was the most important independent risk factor related to postoperative abnormal defecation in intestinal deep endometriosis patients ( < 0.05, OR = 34.133). Infection is the most important independent risk factor related to both postoperative complications (OR = 96.931) and recurrences after conservative surgery (OR = 4.667). Surgery type and age were significantly related to recurrences after conservative surgery.
We recommended conservative operation especially full-thickness disc excision to improve the quality of life of intestinal deep endometriosis patients. In addition, prevention of infection is very important to reduce the postoperative complications rate and the recurrence rate.
本研究旨在评估肠道深部子宫内膜异位症手术治疗中与并发症及长期预后相关的因素,并找出肠道子宫内膜异位症的优化治疗措施。
在中国的一个单中心进行了一项回顾性研究。回顾了2013年1月至2019年8月在浙江大学医学院附属妇产科医院普通妇科接受肠道子宫内膜异位症手术治疗的61名女性的病历。采用多因素回归分析来研究子宫内膜异位症分期和手术步骤(独立危险因素)对并发症(及术后肠道功能障碍)的影响。使用套索回归对临床特征、手术方式、术后治疗、并发症及复发率进行总结和分析。
手术方式是肠道深部子宫内膜异位症患者术后排便异常最重要的独立危险因素(<0.05,OR=34.133)。感染是与术后并发症(OR=96.931)及保守性手术后复发(OR=4.667)均相关的最重要独立危险因素。手术方式和年龄与保守性手术后复发显著相关。
我们推荐采用保守手术,尤其是全层病灶切除术,以提高肠道深部子宫内膜异位症患者的生活质量。此外,预防感染对于降低术后并发症发生率和复发率非常重要。