Peiker G, Müller B, Schwarz A, Dawczynski H, Linke E
Zentralbl Gynakol. 1986;108(24):1487-92.
39 pregnant women, hemoglobin in serum less than or equal to 6,80 mmol/l were treated with Vitaferro, Folicombin and additional vitamins. Test groups were formed by means of randomisation. Hematological and clinicochemical parameters were measured before, as well as 2 and 6 weeks after starting treatment and the results were evaluated.--In the diagnosis of iron deficiency anemia in pregnancy serum iron concentration and iron-binding capacity are sufficient. The diagnosis is proved by an increase of the serum hemoglobin 2 weeks after starting therapy. For the total number of patients an increase of hemoglobin could be proved 2- and 6 weeks after starting therapy. However, the 3 chosen therapeutic methods did not show any differences in statistically proved values in form of therapeutic results. This is, in our view, due to given deviation and the specific character of the test group. During pregnancy iron deficiency anemia should be treated by doses more than 100 mg iron per day. Normalization of the hemoglobin under iron substitution is no indication for immediate interruption of the treatment.