Zeng Qingwen, Liu Yangyang
Children Healthcare Center of Shiyan Maternal and Child Health Care Hospital, Shiyan, China.
Children Rehabilitation Department of Shiyan Maternal and Child Health Care Hospital, Shiyan, China.
Evid Based Complement Alternat Med. 2022 Jun 21;2022:4677795. doi: 10.1155/2022/4677795. eCollection 2022.
The aim is to evaluate the effects of routine health care combined with oral vitamin D on linear growth in 5-year-old children.
The 5-year-old children who received routine health care in Shiyan Maternal and Child Health Care Hospital from January 2019 to January 2021 were retrospectively analyzed. They were divided into the supplement group and the non-supplement group according to whether or not they received oral vitamin D, and reasons for not taking oral vitamin D and its influence on children's linear growth were analyzed.
A total of 368 children were enrolled, including 228 children in the supplement group, accounting for 61.96%. The analysis of the influencing factors of vitamin D supplementation showed that the proportion of children with well-educated parents and living in cities and towns was higher (all < 0.05). Comparing the general situation of children in the two groups, it was found that the height, weight, and head circumference of children in the supplement group were notably higher than those in the non-supplement group (all < 0.05). At age 4 and 5, the height of the supplement group was significantly higher than that of the non-supplement group (all < 0.001). Linear analysis showed that the relationship between height and age in the supplement group was (height, cm) = 10.07 × (age, years) + 61.18, while that in the non-supplement group was (height, cm) = 8.296 × (age, years) + 62.81, with significant difference (all < 0.05). Serum 25-hydroxyvitamin D concentration in the supplement group was significantly higher than that in the non-supplement group, and the proportion of children ≥75 nmol/L was evidently higher than that in the supplement group (all < 0.05). In addition, the incidence of vitamin D-related hypercalcemia in the supplement group was significantly higher than that in the non-supplement group (all < 0.05).
There are still more children without vitamin D supplement, which is closely related to their parents' education background and place of residence. Additionally, vitamin D supplementation can promote growth and improve 25-hydroxyvitamin D levels in children, but with the risk of related complications.
评估常规保健联合口服维生素D对5岁儿童线性生长的影响。
回顾性分析2019年1月至2021年1月在十堰市妇幼保健院接受常规保健的5岁儿童。根据是否口服维生素D将其分为补充组和非补充组，并分析未口服维生素D的原因及其对儿童线性生长的影响。
共纳入368例儿童，其中补充组228例，占61.96%。维生素D补充影响因素分析显示，父母受教育程度高及居住在城镇的儿童比例更高（均P<0.05）。比较两组儿童一般情况，发现补充组儿童身高、体重、头围均显著高于非补充组（均P<0.05）。在4岁和5岁时，补充组儿童身高显著高于非补充组（均P<0.001）。线性分析显示，补充组身高与年龄的关系为（身高，cm）=10.07×（年龄，岁）+61.18，而非补充组为（身高，cm）=8.296×（年龄，岁）+62.81，差异有统计学意义（均P<0.05）。补充组血清25-羟维生素D浓度显著高于非补充组，≥75 nmol/L的儿童比例明显高于非补充组（均P<0.05）。此外，补充组维生素D相关高钙血症发生率显著高于非补充组（均P<0.05）。
仍有较多儿童未补充维生素D，这与其父母的教育背景和居住地密切相关。此外，补充维生素D可促进儿童生长并提高25-羟维生素D水平，但存在相关并发症风险。
Zotero 插件