Puras D K
Zh Nevropatol Psikhiatr Im S S Korsakova. 1987;87(3):389-92.
The author studied the prevalence of severe mental retardation in Vilnyus and considered the status of its etiological and clinical differentiation. A total of 224 cases of oligophrenia were identified among children aged 4-13 years which constituted a populational rate of 0.31% in the above age group. A marked predominance of males among the cases with undifferentiated forms was ascertained, which is probably due to the accumulation in this group of X-chromosome-linked mental retardation. Cytogenetic examination of 20 suspected cases revealed the syndrome of a fragile X chromosome in 4 patients.
作者研究了维尔纽斯严重智力迟钝的患病率，并考虑了其病因学和临床鉴别诊断情况。在4至13岁的儿童中，共确诊224例智力低下病例，在上述年龄组中的人群患病率为0.31%。未分化型病例中男性明显居多，这可能是由于该组中X染色体连锁智力迟钝的累积。对20例疑似病例进行细胞遗传学检查，发现4例患者存在脆性X染色体综合征。
