Burov Iu V, Treskov V G, Vedernikova N N, Sheveleva O S
Zh Nevropatol Psikhiatr Im S S Korsakova. 1987;87(3):424-8.
The study covered 54 males with stage II alcoholism with various types of the abstinence syndrome in the state of acute abstinence (the first day of alcohol discontinuation) and 10 healthy males. The baseline cortisol levels were radioimmunoassayed and the dexamethasone suppression test (DST) was performed. The baseline levels of cortisol were elevated in all 4 types of the abstinence syndrome, being significantly higher in the dysphoric type. An abnormal DST was observed in 25 patients (46.3%) and was significantly more frequent in the depressive and schizothymovegetative types of the abstinence syndrome as against the asthenovegetative and dysphoric types and control. Psychometric examination revealed certain differences in the degree of abstinence symptoms and some clinical characteristics of the disease between patients with a pathologic and a normal DST.
该研究涵盖了54名处于急性戒酒期（戒酒第一天）的II期酒精中毒男性患者，他们存在各种类型的戒酒综合征，以及10名健康男性。采用放射免疫分析法检测基础皮质醇水平，并进行地塞米松抑制试验（DST）。在所有4种戒酒综合征类型中，基础皮质醇水平均升高，其中烦躁型显著更高。25名患者（46.3%）观察到DST异常，与虚弱植物神经型、烦躁型及对照组相比，抑郁型和分裂性植物神经型戒酒综合征中DST异常更为常见。心理测量检查显示，DST病理型和正常型患者在戒酒症状程度和疾病的一些临床特征方面存在一定差异。
