• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

COVID-19 大流行期间非复杂性急性阑尾炎的管理:阑尾切除术还是非手术治疗?

Management of uncomplicated acute appendicitis during the COVID-19 pandemic: Appendectomy or non-surgical treatment?

机构信息

Department of General Surgery, Kahramanmaraş Elbistan State Hospital, Kahramanmaraş-Türkiye.

出版信息

Ulus Travma Acil Cerrahi Derg. 2022 Jul;28(7):894-899. doi: 10.14744/tjtes.2021.45944.

DOI:10.14744/tjtes.2021.45944
PMID:35775671
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10493843/
Abstract

BACKGROUND

This study aims to compare medical treatment and appendectomy in patients diagnosed with uncomplicated acute appendicitis during the COVID-19 pandemic.

METHODS

Retrospectively analyzed were the data of 80 patients who received medical or surgical treatment for uncomplicated acute appendicitis between March 15, 2020, and August 31, 2020. The demographic characteristics of the patients, length of hospital stay, physical examination and radiology findings, laboratory results, and any complications were recorded. Patients were divided into two groups depending on the mode of treatment, as surgical and non-surgical.

RESULTS

Forty patients were given medical treatment and 40 patients were directly operated on for appendicitis. Of the 40 patients who received medical treatment, 8 (20%) ended up requiring an operation due to recurrence. The mean duration of hospitalization was 2 days (range: 1-3), and the mean follow-up duration was 285.35±65.66 days (range: 101-379). The white blood cell count was significantly higher in the surgical group (p=0.004), and the length of hospital stay was longer in the non-surgical group (p<0.001). The prevalence of post-operative complications was similar for patients who underwent appendectomy directly on admission or after recurrence (p=1.000). Among the patients who received medical treatment, the most important predictors of requiring surgery were the red cell distribution width and increased appendix diameter in computed tomography (p<0.05).

CONCLUSION

Medical treatment is an effective alternative in patients with uncomplicated appendicitis. Even in the case of a recurrence in follow-up, surgery due to a potential recurrence is not associated with an increased rate of complication compared to direct surgery.

摘要

背景

本研究旨在比较 COVID-19 大流行期间诊断为单纯性急性阑尾炎患者的内科治疗和阑尾切除术。

方法

回顾性分析了 2020 年 3 月 15 日至 2020 年 8 月 31 日期间接受单纯性急性阑尾炎内科或手术治疗的 80 例患者的数据。记录了患者的人口统计学特征、住院时间、体格检查和影像学发现、实验室结果以及任何并发症。根据治疗方式将患者分为手术组和非手术组。

结果

40 例患者接受内科治疗,40 例患者直接手术治疗阑尾炎。在接受内科治疗的 40 例患者中,有 8 例(20%)因复发而最终需要手术。住院时间的平均值为 2 天(范围:1-3 天),平均随访时间为 285.35±65.66 天(范围:101-379 天)。手术组的白细胞计数明显较高(p=0.004),非手术组的住院时间较长(p<0.001)。直接入院或复发后行阑尾切除术的患者术后并发症发生率相似(p=1.000)。在内科治疗的患者中,需要手术的最重要预测因素是红细胞分布宽度和 CT 检查中阑尾直径增加(p<0.05)。

结论

内科治疗是单纯性阑尾炎患者的有效替代方法。即使在随访中复发,与直接手术相比,因潜在复发而进行的手术也不会增加并发症的发生率。

相似文献

1
Management of uncomplicated acute appendicitis during the COVID-19 pandemic: Appendectomy or non-surgical treatment?COVID-19 大流行期间非复杂性急性阑尾炎的管理:阑尾切除术还是非手术治疗?
Ulus Travma Acil Cerrahi Derg. 2022 Jul;28(7):894-899. doi: 10.14744/tjtes.2021.45944.
2
Five-Year Follow-up of Antibiotic Therapy for Uncomplicated Acute Appendicitis in the APPAC Randomized Clinical Trial.APPAC 随机临床试验中单纯性急性阑尾炎抗生素治疗的 5 年随访。
JAMA. 2018 Sep 25;320(12):1259-1265. doi: 10.1001/jama.2018.13201.
3
Impact of the COVID-19 pandemic on appendicitis treatment in Germany-a population-based analysis.COVID-19 大流行对德国阑尾炎治疗的影响-基于人群的分析。
Langenbecks Arch Surg. 2021 Mar;406(2):377-383. doi: 10.1007/s00423-021-02081-4. Epub 2021 Jan 9.
4
Factors affecting the length of hospital stay after laparoscopic appendectomy: A single center study.腹腔镜阑尾切除术住院时间的影响因素:单中心研究。
PLoS One. 2020 Dec 9;15(12):e0243575. doi: 10.1371/journal.pone.0243575. eCollection 2020.
5
Antibiotics-first strategy for uncomplicated acute appendicitis in adults is associated with increased rates of peritonitis at surgery. A systematic review with meta-analysis of randomized controlled trials comparing appendectomy and non-operative management with antibiotics.成人单纯性急性阑尾炎的抗生素优先策略与手术时腹膜炎发生率增加相关。一项对比较阑尾切除术与抗生素非手术治疗的随机对照试验进行系统评价和荟萃分析。
Surgeon. 2017 Oct;15(5):303-314. doi: 10.1016/j.surge.2017.02.001. Epub 2017 Mar 9.
6
Conservative antibiotic treatment of pediatric acute uncomplicated appendicitis during the COVID-19 pandemic: a prospective comparative cohort study.COVID-19 大流行期间儿童急性单纯性阑尾炎的保守抗生素治疗:一项前瞻性对比队列研究。
Pediatr Surg Int. 2022 Dec 23;39(1):60. doi: 10.1007/s00383-022-05344-3.
7
Acute Appendicitis: Still a Surgical Disease? Results from a Propensity Score-Based Outcome Analysis of Conservative Versus Surgical Management from a Prospective Database.急性阑尾炎:仍是一种外科疾病?基于倾向评分的前瞻性数据库中保守治疗与手术治疗结果分析
World J Surg. 2017 Nov;41(11):2697-2705. doi: 10.1007/s00268-017-4094-4.
8
Laparoscopic Appendectomy for Complicated Acute Appendicitis in the Elderly: A Single-center Experience.老年复杂性急性阑尾炎的腹腔镜阑尾切除术:单中心经验
Surg Laparosc Endosc Percutan Tech. 2017 Oct;27(5):366-368. doi: 10.1097/SLE.0000000000000447.
9
Covid-19 Pandemic Strategy for Treatment of Acute Uncomplicated Appendicitis with Antibiotics- Risk Categorization and Shared Decision-Making.新冠疫情时期抗生素治疗急性单纯性阑尾炎的策略-风险分类和共同决策。
J Pediatr Surg. 2023 Jul;58(7):1285-1290. doi: 10.1016/j.jpedsurg.2023.02.052. Epub 2023 Feb 23.
10
Decision-making changes for patients and medical personnel in the management of acute appendicitis during the COVID-19 pandemic.COVID-19 大流行期间急性阑尾炎管理中患者和医务人员决策的变化。
BMC Emerg Med. 2022 Oct 24;22(1):170. doi: 10.1186/s12873-022-00727-0.

本文引用的文献

1
Management of appendicitis during COVID-19 pandemic; short-term outcomes.COVID-19 大流行期间阑尾炎的处理;短期结果。
Scott Med J. 2020 Nov;65(4):144-148. doi: 10.1177/0036933020956316. Epub 2020 Sep 2.
2
Current opinions and practices for the management of acute appendicitis: an international survey.目前急性阑尾炎管理的观点和实践:一项国际调查。
Ir J Med Sci. 2021 May;190(2):749-754. doi: 10.1007/s11845-020-02349-6. Epub 2020 Aug 27.
3
International guidelines and recommendations for surgery during Covid-19 pandemic: A Systematic Review.国际新冠疫情期间手术指南和建议:系统综述。
Int J Surg. 2020 Jul;79:180-188. doi: 10.1016/j.ijsu.2020.05.061. Epub 2020 May 23.
4
Recommendations for Trauma and Emergency General Surgery Practice During COVID-19 Pandemic.2019冠状病毒病大流行期间创伤与普通急诊外科实践的建议
Ulus Travma Acil Cerrahi Derg. 2020 Apr;26(3):335-342. doi: 10.14744/tjtes.2020.79954.
5
Accuracy of Mean Platelet Volume (MPV) and Red Cell Distribution Width (RDW) for the Diagnosis of Acute Appendicitis: Evaluation of Possible New Biomarkers.平均血小板体积(MPV)和红细胞分布宽度(RDW)在急性阑尾炎诊断中的准确性:对可能的新型生物标志物的评估
Adv J Emerg Med. 2019 Aug 20;4(2):e20. doi: 10.22114/ajem.v0i0.194. eCollection 2020 Spring.
6
Diagnosis and treatment of acute appendicitis: 2020 update of the WSES Jerusalem guidelines.急性阑尾炎的诊断和治疗:WSES 耶路撒冷指南 2020 年更新版。
World J Emerg Surg. 2020 Apr 15;15(1):27. doi: 10.1186/s13017-020-00306-3.
7
Guidelines for Laboratory Diagnosis of Coronavirus Disease 2019 (COVID-19) in Korea.韩国 2019 冠状病毒病(COVID-19)实验室诊断指南。
Ann Lab Med. 2020 Sep;40(5):351-360. doi: 10.3343/alm.2020.40.5.351.
8
The value of ischemia-modified albumin and oxidative stress markers in the diagnosis of acute appendicitis in adults.缺血修饰白蛋白和氧化应激标志物在成人急性阑尾炎诊断中的价值。
Am J Emerg Med. 2019 Nov;37(11):2097-2101. doi: 10.1016/j.ajem.2019.03.005. Epub 2019 Mar 7.
9
Readmission after antibiotic management of uncomplicated acute appendicitis in adults: prospective study.成人单纯性急性阑尾炎抗生素管理后的再入院:前瞻性研究。
Eur J Trauma Emerg Surg. 2020 Aug;46(4):841-846. doi: 10.1007/s00068-018-1038-0. Epub 2018 Oct 26.
10
Five-Year Follow-up of Antibiotic Therapy for Uncomplicated Acute Appendicitis in the APPAC Randomized Clinical Trial.APPAC 随机临床试验中单纯性急性阑尾炎抗生素治疗的 5 年随访。
JAMA. 2018 Sep 25;320(12):1259-1265. doi: 10.1001/jama.2018.13201.