Hallak Abdulaziz, Ranjbar Reza, Nourinezhad Jamal
Department of Basic Sciences, Faculty of Veterinary Medicine, Shahid Chamran University of Ahvaz, Ahvaz, Iran.
Division of Anatomy and Embryology, Department of Basic Sciences, Faculty of Veterinary Medicine, Shahid Chamran University of Ahvaz, P.O. Box 61357-13839, Ahvaz, Iran.
Anat Sci Int. 2023 Jan;98(1):107-122. doi: 10.1007/s12565-022-00678-3. Epub 2022 Jul 1.
This study aimed to investigate the arterial arrangement of the spinal cord in Syrian hamsters, and to identify differences and similarities to humans and experimental animals that are mostly used as models in studies into ischemic spinal cord injuries. This observational anatomical study was conducted on 20 adult Syrian hamsters using dissection and corrosion casting technique. The general anatomy of the arterial blood supply of spinal cord was obtained and noted as follows: (1) high variability in the level of the origin of right and left vertebral arteries, (2) the independent origin of dorsal intercostal arteries, (3) origin of lumbar arteries as a common trunk with right and left divisions, (4) presence of dorsal and ventral radicular branches in both sides of the cervical spinal cord with almost the same frequency, (5) greater presence of ventral and dorsal radicular branches in the left side of the thoracolumbar spinal cord, (6) two dorsal spinal arteries originating from the posterior inferior cerebellar arteries and extending to the caudal end of the thoracic spinal cord, (7) continuous ventral spinal artery originating from both vertebral arteries and extending to the conus medularis, and (8) presence of the artery of Adamkiewicz in the thoracic region of the spinal cord. From comparative anatomy viewpoints, the arteries supplying the spinal cord of Syrian hamsters exhibit many similarities with humans, laboratory rodents, and rabbits in many aspects compared to dogs, cats, and pigs. Overall, Syrian hamsters can be used as a proposed model in experimental studies of the spinal cord ischemia.
本研究旨在调查叙利亚仓鼠脊髓的动脉分布，并确定其与人类以及在脊髓缺血性损伤研究中最常作为模型使用的实验动物之间的异同。本观察性解剖学研究使用解剖和铸型技术对20只成年叙利亚仓鼠进行。获得并记录了脊髓动脉血液供应的一般解剖结构如下：（1）左右椎动脉起源水平高度可变；（2）肋间后动脉独立起源；（3）腰动脉以共同干形式起源，分为左右两支；（4）颈脊髓两侧背根和腹根分支出现频率几乎相同；（5）胸腰段脊髓左侧腹根和背根分支较多；（6）两条脊髓背动脉起源于小脑下后动脉，延伸至胸段脊髓尾端；（7）脊髓腹动脉由双侧椎动脉起源并延伸至脊髓圆锥；（8）脊髓胸段存在Adamkiewicz动脉。从比较解剖学的角度来看，与狗、猫和猪相比，供应叙利亚仓鼠脊髓的动脉在许多方面与人类、实验啮齿动物和兔子有许多相似之处。总体而言，叙利亚仓鼠可作为脊髓缺血实验研究的一种推荐模型。
