District Nurse Student Apprentice, Manchester Metropolitan University Business School.
Br J Community Nurs. 2022 Jul 2;27(7):328-335. doi: 10.12968/bjcn.2022.27.7.328.
In the UK, Parkinson's disease (PD) is estimated to affect an annual incidence of 15-20 per 100 000 of the population over the age of 60. Service users living with advanced-stage PD require the use of apomorphine, which is generally used to control symptoms. The district nursing service plays a key role in monitoring and in the administration of apomorphine therapy. Although apomorphine is effective, skin problems such as nodules are commonly reported adverse events that can complicate efficiency of treatment. A sublingual delivery route to apomorphine has been known for years as a feasible alternative to subcutaneous route. Collaboration between the multidisciplinary team is essential to meet the complex needs of service users with advanced PD. However, due to the increase in demands of the district nurse service, this time crucial intervention can be unpredictable to meet. An alternative route can enable district nurses to become less task-orientated. However, an increased risk of oral cavity related adverse events should be taken into consideration with the sublingual administration of apomorphine.
在英国，帕金森病（PD）的发病率估计为每年每 10 万 60 岁以上人群中 15-20 例。处于晚期 PD 的患者需要使用阿扑吗啡，阿扑吗啡通常用于控制症状。地区护理服务在监测和管理阿扑吗啡治疗方面发挥着关键作用。尽管阿扑吗啡有效，但皮肤结节等常见不良反应会使治疗效率复杂化。多年来，舌下给药途径作为皮下途径的可行替代方案已为人所知。多学科团队之间的协作对于满足晚期 PD 患者的复杂需求至关重要。然而，由于地区护士服务需求的增加，这种关键的干预措施可能难以预测。替代途径可以使地区护士的工作不再以任务为导向。然而，与舌下给予阿扑吗啡相关的口腔相关不良事件的风险增加应加以考虑。
