Department of Geriatrics, West China Hospital, West China School of Nursing, Sichuan University, Chengdu, Sichuan, China.
West China School of Nursing, Sichuan University/Innovation Center of Nursing Research, Nursing Key Laboratory of Sichuan Province, West China Hospital, Sichuan University, China.
Medicine (Baltimore). 2022 Jul 1;101(26):e29737. doi: 10.1097/MD.0000000000029737.
As the population continues to age, dementia is becoming a huge social, economic, and healthcare burden. However, the risk factors for in-hospital death in elderly patients over 65 years of age with dementia are not well understood. Identifying factors that affect their prognosis could help clinicians with scientific decision-making. To examine the risk factors for in-hospital death in elderly patients over 65 years of age with dementia in the Geriatric Department of West China Hospital. In this retrospective, cross-sectional study, we analyzed inpatients aged ≥65 years with dementia between 2010 and 2016 using electronic medical records from the Information Center of West China Hospital. The risk factors for death were assessed using multivariable logistic regression. Out of a total of 2986 inpatients with dementia, 3.4% died. Patient deaths were related to digestive diseases, respiratory diseases, circulatory diseases, urinary diseases, and chronic obstructive pulmonary disease, whereas patient survival was associated with osteoporosis and Parkinson disease. Patients with a mean length of hospital stay of ≥60 days had an increased risk of death (all P <.05). In the multiple logistic regression analysis, age ≥80 years, digestive diseases, respiratory diseases, urinary diseases, diabetes, chronic obstructive pulmonary disease, and ≥7 comorbidities were risk factors for death. Mortality in hospitalized older patients with dementia is low, but some risk factors may be easily ignored. These findings could raise awareness among clinicians and caregivers about risk factors in hospitalized older patients, particularly hospitalized elderly patients with multiple comorbidities. Therefore, to reduce mortality, early prevention and management of potential risks are necessary.
随着人口老龄化的加剧,痴呆症成为了一个巨大的社会、经济和医疗保健负担。然而,65 岁以上痴呆老年患者住院期间死亡的风险因素尚未得到充分认识。确定影响其预后的因素有助于临床医生做出科学决策。本研究旨在探讨华西医院老年科 65 岁以上痴呆老年患者住院期间死亡的风险因素。这是一项回顾性、横断面研究,我们分析了 2010 年至 2016 年华西医院信息中心电子病历中年龄≥65 岁且患有痴呆的住院患者。使用多变量逻辑回归评估死亡的风险因素。在总共 2986 例痴呆住院患者中,有 3.4%的患者死亡。患者死亡与消化疾病、呼吸疾病、循环系统疾病、泌尿系统疾病和慢性阻塞性肺疾病有关,而患者存活与骨质疏松症和帕金森病有关。平均住院时间≥60 天的患者死亡风险增加(均 P<.05)。在多变量逻辑回归分析中,年龄≥80 岁、消化系统疾病、呼吸系统疾病、泌尿系统疾病、糖尿病、慢性阻塞性肺疾病和≥7 种合并症是死亡的危险因素。住院痴呆老年患者的死亡率较低,但一些风险因素可能容易被忽视。这些发现可能会引起临床医生和护理人员对住院老年患者风险因素的重视,尤其是对患有多种合并症的住院老年痴呆患者。因此,为了降低死亡率,有必要早期预防和管理潜在风险。