Universty of Health and Science Sultan Abdulhamid Han Training and Research Hospital Istanbul, Estambul, Turkey.
Universty of Health and Science Sultan Abdulhamid Han Training and Research Hospital Istanbul, Estambul, Turkey.
Actas Urol Esp (Engl Ed). 2022 Sep;46(7):407-412. doi: 10.1016/j.acuroe.2021.11.006. Epub 2022 Jun 28.
The clinical symptoms in benign prostatic hyperplasia (BPH) are directly proportional to prostate volume. We aimed to show whom and when to intervene in a noninvasive way, correlating the patient's subjective symptoms with objective diagnostic tools.
International Prostate Symptom Score (IPSS) was evaluated in patients who consulted the urology outpatient clinic for the first time with lower urinary tract symptoms (LUTS). Subsequently, PSA, urea, creatinine, complete urinalysis, uroflowmetry, urinary tract ultrasound and non-contrast lower abdominal computed tomography (CT) examinations were requested. Prostate central (transitional zone) zone and peripheral zone HU scores, prostatic urethral length and bladder wall Hounsfield units (HU) scores were recorded by using computed tomography (CT). The ellipsoid formula was used for ultrasonographic and tomographic measurements of prostate size (anteroposterior diameter × transverse diameter × longitudinal diameter × 0.52).
A statistically significant negative correlation was found between the prostate peripheral zone/central zone HU ratio and the maximum flow rate measured in the uroflowmetry test.
This is the first study in the literature to evaluate the correlation between voiding parameters such as Qmax, Qave and IPSS scores, and prostate and bladder wall HU scores obtained by computed tomography examination in BPH patients. A significant relationship has been detected between the peripheral zone/central zone HU ratio and Q max. Additional studies with larger patient populations could better clarify the contribution of HU in the diagnosis of BPH and treatment decision making of these patients.
良性前列腺增生（BPH）的临床症状与前列腺体积成正比。我们旨在通过将患者的主观症状与客观诊断工具相关联，以非侵入性的方式展示何时以及向谁进行干预。
首次因下尿路症状（LUTS）到泌尿科门诊就诊的患者，评估国际前列腺症状评分（IPSS）。随后，要求进行 PSA、尿素、肌酐、全尿分析、尿流率、尿路超声和非对比下腹部计算机断层扫描（CT）检查。通过 CT 记录前列腺中央（移行区）区和外周区 HU 评分、前列腺尿道长度和膀胱壁 HU 评分。使用超声和 CT 测量前列腺体积（前后径×横径×长径×0.52）。
在尿流率测试中，前列腺外周区/中央区 HU 比值与最大流量之间存在统计学显著负相关。
这是文献中第一项评估 BPH 患者的排尿参数（如最大流量 Qmax、平均流量 Qave 和 IPSS 评分）与通过 CT 检查获得的前列腺和膀胱壁 HU 评分之间相关性的研究。在外周区/中央区 HU 比值与 Qmax 之间检测到显著相关性。更大的患者人群的进一步研究可以更好地阐明 HU 在 BPH 诊断和这些患者的治疗决策中的作用。
