Castelli Barbara, Marrani Edoardo, Fusco Eleonora, Chiara Caporalini, Pagnini Ilaria, Simonini Gabriele
Rheumatology Unit, AOU Meyer Children's Hospital, Florence, Italy.
Division of Pathological Anatomy, AOU Meyer Children's Hospital, University of Florence, Florence, Italy.
Pediatr Dermatol. 2022 Nov;39(6):946-949. doi: 10.1111/pde.15077. Epub 2022 Jul 2.
Immunoglobulin A vasculitis (IgAV) is the most common childhood vasculitis affecting small vessels. No clear recommendations are available for severe pediatric cases, and until now, anti-TNF agents have had a limited role in IgAV management. In this report, we describe a pediatric case of severe IgAV, successfully treated with combined therapy including the anti-TNF, infliximab.
免疫球蛋白A血管炎（IgAV）是影响小血管的最常见儿童血管炎。对于重症儿科病例尚无明确的推荐治疗方法，迄今为止，抗TNF药物在IgAV的治疗中作用有限。在本报告中，我们描述了1例重症IgAV儿科病例，该病例通过包括抗TNF药物英夫利昔单抗在内的联合治疗获得成功治愈。
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