Department of Obstetrics and Gynecology, Chi Mei Medical Center, Tainan, Taiwan.
Department of Obstetrics and Gynecology, Changhua Christian Hospital, Changhua, Taiwan.
Taiwan J Obstet Gynecol. 2022 Jul;61(4):601-605. doi: 10.1016/j.tjog.2021.08.005.
The aim of this study was to review the reproductive outcomes of women with a cesarean scar pregnancy (CSP) treated with dilation and curettage (D&C) after uterine artery embolization (UAE).
This was a retrospective study to review women who received UAE followed by D&C for CSP between January 2010 and December 2019 at the Changhua Christian Hospital, Changhua in Taiwan. Data were collected from both electronic and paper medical records. Patients were contact via phone call to follow up reproductive outcomes between January 2021 and March 2021. These subsequent reproductive outcomes (including pregnancy rate, secondary infertility rate, miscarriage rate, live birth rate, and recurrent CSP rate) were recorded and analyzed.
A total of 53 cases of women who received UAE followed by D&C for CSP were identified. The women's average age was 34.8 ± 5.1 years. The mean gestational age at diagnosis was 6.2 ± 1.1 weeks. The mean level for human chorionic gonadotropin was 23,407.7 ± 29,105.5 mIU/ml. The average of blood loss during D&C was 19.2 ± 43.6 ml. The average hospitalization time after D&C was 3.5 ± 1.1 days. Of the 53 cases, 10 patients were lost to follow-up and 43 patients agreed to follow-up on reproductive outcomes in 2021. Twenty-three patients who desired to conceive were analyzed. Nineteen out of these 23 women (82.6%) succeeded in conceiving again and gave birth to 15 healthy babies (78.9%). Only one woman (1/19, 5.3%) experienced recurrence of CSP. The average time interval between previous CSP treatment and subsequent conception was 10.4 ± 6.7 months.
UAE combined with curettage treatment in CSP patients results in a positive rate of subsequent pregnancy outcomes. This minimally invasive procedure may be considered as one of the treatment options for CSP, as it enables preservation of fertility after treatment.
本研究旨在回顾因剖宫产瘢痕妊娠(CSP)接受子宫动脉栓塞术(UAE)后行刮宫术(D&C)治疗的女性的生殖结局。
这是一项回顾性研究,回顾了 2010 年 1 月至 2019 年 12 月在台湾彰化基督教医院接受 UAE 联合 D&C 治疗 CSP 的患者。数据来自电子和纸质病历。通过电话联系患者,在 2021 年 1 月至 2021 年 3 月之间随访生殖结局。记录并分析这些后续生殖结局(包括妊娠率、继发性不孕率、流产率、活产率和复发性 CSP 率)。
共确定了 53 例因 CSP 接受 UAE 联合 D&C 治疗的女性。患者的平均年龄为 34.8±5.1 岁。诊断时的平均妊娠龄为 6.2±1.1 周。人绒毛膜促性腺激素的平均水平为 23407.7±29105.5 mIU/ml。D&C 期间的平均出血量为 19.2±43.6ml。D&C 后平均住院时间为 3.5±1.1 天。53 例中,10 例患者失访,43 例患者同意在 2021 年随访生殖结局。分析了 23 例有生育要求的患者。这 23 例患者中有 19 例(82.6%)成功再次怀孕并生下 15 名健康婴儿(78.9%)。仅 1 例患者(1/19,5.3%)发生 CSP 复发。上次 CSP 治疗与后续受孕的平均时间间隔为 10.4±6.7 个月。
UAE 联合 D&C 治疗 CSP 患者,后续妊娠结局阳性率较高。这种微创治疗方法可能被视为 CSP 的治疗选择之一,因为它可以在治疗后保留生育能力。