Gynecologic Oncology Unit, Department of Obstetrics and Gynecology, Faculty of Medicine, Prince of Songkla University, Songkhla, 90110, Thailand.
Department of Obstetrics and Gynecology, Faculty of Medicine, Prince of Songkla University, Songkhla, 90110, Thailand.
Taiwan J Obstet Gynecol. 2022 Jul;61(4):657-662. doi: 10.1016/j.tjog.2022.03.042.
To evaluate the prevalence of appendiceal tumors in patients diagnosed with mucinous ovarian tumors and to determine factors associated with coexisting appendiceal tumors.
Retrospective review of all patients who were diagnosed with mucinous ovarian tumors and underwent an appendectomy during surgery between January 2002 and June 2017 was performed. Univariate and multivariate logistic regression analyses were used to identify risk factors for coexisting appendiceal tumors.
A total of 303 patients with mucinous ovarian tumors who underwent appendectomy were identified, including 77 (25.4%) mucinous cystadenoma and 226 (74.6%) mucinous borderline tumor or carcinoma. Twenty-one (6.9%) had coexisting appendiceal tumors including 8 that were primary appendiceal mucinous adenocarcinomas, 6 low-grade appendiceal mucinous neoplasms, 6 secondary appendiceal metastasis from the ovary, and one hyperplastic polyp. None of mucinous cystadenoma had coexisting appendiceal tumors. Multivariate analysis revealed advanced age ≥50 years, previous rupture of ovarian tumors, abdominal extension of tumors, and grossly abnormal appendix were independent factors for coexisting appendiceal tumors.
Prevalence of coexisting appendiceal tumors in mucinous ovarian tumors was not uncommon. The risk factors were grossly abnormal appendix, abdominal extension of tumor, previous rupture of ovarian tumors, and advanced age.
评估诊断为黏液性卵巢肿瘤的患者中阑尾肿瘤的患病率，并确定与并存阑尾肿瘤相关的因素。
对 2002 年 1 月至 2017 年 6 月期间行手术且同时诊断为黏液性卵巢肿瘤并行阑尾切除术的所有患者进行回顾性分析。采用单因素和多因素逻辑回归分析来确定并存阑尾肿瘤的危险因素。
共确定了 303 例行阑尾切除术的黏液性卵巢肿瘤患者，其中 77 例（25.4%）为黏液性囊腺瘤，226 例（74.6%）为交界性或癌性黏液性肿瘤。21 例（6.9%）存在并存的阑尾肿瘤，包括 8 例原发性阑尾黏液性腺癌、6 例低级别阑尾黏液性肿瘤、6 例来自卵巢的继发性阑尾转移和 1 例增生性息肉。无黏液性囊腺瘤存在并存的阑尾肿瘤。多因素分析显示，年龄≥50 岁、卵巢肿瘤破裂史、肿瘤腹腔扩散和阑尾大体异常是并存阑尾肿瘤的独立危险因素。
在黏液性卵巢肿瘤中并存阑尾肿瘤的患病率并不少见。危险因素包括阑尾大体异常、肿瘤腹腔扩散、卵巢肿瘤破裂史和高龄。
