Miller C D, Songer J R, Sullivan J F
Am Ind Hyg Assoc J. 1987 Mar;48(3):271-5. doi: 10.1080/15298668791384733.
The National Animal Disease Center's experience with personnel exposure or infection with pathogenic agents is summarized. A total of 128 laboratory-associated exposures to infectious disease agents were reported. Of these exposures, 103 resulted from known accidents. The other 25 were identified only after the development of clinical or serological manifestations of infection. Thirty-four cases of laboratory-acquired infections were reviewed. Class 3 organisms--Chlamydia sp., Brucella sp. and Mycobacterium sp.--were responsible for 76% of the infections encountered, with Brucella sp. incriminated most frequently. The most commonly reported cause of exposure was associated with hypodermic syringe use. Unknown routes of exposure, presumed to be aerosol related, were the overwhelming explanation involved in the laboratory-associated infections.
总结了国家动物疾病中心工作人员接触或感染病原体的经历。共报告了128起与实验室相关的传染病病原体接触事件。在这些接触事件中，103起是由已知事故导致的。另外25起是在出现感染的临床或血清学表现后才被发现的。回顾了34例实验室获得性感染病例。3类病原体——衣原体属、布鲁氏菌属和分枝杆菌属——导致了所遇到感染病例的76%，其中布鲁氏菌属最为常见。报告的最常见接触原因与皮下注射器的使用有关。未知的接触途径，推测与气溶胶有关，是实验室相关感染的主要原因。
