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一名接受过治疗的丙型肝炎肝硬化患者出现脑病合并肾衰竭的罕见病因。

An unusual cause of encephalopathy with renal failure in a patient with treated HCV cirrhosis.

作者信息

Kalal Chetan, Wagh Adinath, Patel Atif, Joshi Harshad, Jain Samit, Deshpande Rushi, Bhatia Shobna, Bhatt Chetan

机构信息

Department of Gastroenterology, Sir HN Reliance Hospital and Research Centre, Mumbai, India.

Department of Nephrology, Sir HN Reliance Hospital and Research Centre, Mumbai, India.

出版信息

Hepatol Forum. 2021 Jan 8;2(1):34-35. doi: 10.14744/hf.2020.2020.0020. eCollection 2021 Jan.

Abstract

A 63-year-old teetotaller male, previously treated for hepatitis C-related compensated cirrhosis, presented with acute-onset encephalopathy with no focal neurological deficit and stable vitals. Investigations revealed elevated serum creatinine (2.94 mg/dL), hypercalcemia, hypophosphatemia, and high serum PTH levels. He was diagnosed with right parathyroid adenoma (1.3×1.2×0.7 cm) with the help of a neck ultrasound. His encephalopathy and renal failure persisted despite adequate IV fluids, calcitonin, and bisphosphonates. Urgent hemi-parathyroidectomy was performed on day four, following which he recovered completely.

摘要

一名63岁的男性戒酒者,既往因丙型肝炎相关性代偿期肝硬化接受过治疗,此次出现急性起病的脑病,无局灶性神经功能缺损,生命体征稳定。检查发现血清肌酐升高(2.94 mg/dL)、高钙血症、低磷血症以及血清甲状旁腺激素水平升高。借助颈部超声,他被诊断为右甲状旁腺腺瘤(1.3×1.2×0.7 cm)。尽管给予了充足的静脉补液、降钙素和双膦酸盐治疗,他的脑病和肾衰竭仍持续存在。在第四天进行了紧急半甲状旁腺切除术,术后他完全康复。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0592/9138926/1e25f658cac7/hf-2-34-g001.jpg

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