Liu Yin, Lu Liyan, Li Fengfang, Chen Yu-Chen
Department of Radiology, Nanjing First Hospital, Nanjing Medical University, Nanjing, China.
Front Neurosci. 2022 Jun 17;16:923662. doi: 10.3389/fnins.2022.923662. eCollection 2022.
Mild traumatic brain injury (mTBI) accounts for more than 80% of the total number of TBI cases. The mechanism of injury for patients with mTBI has a variety of neuropathological processes. However, the underlying neurophysiological mechanism of the mTBI is unclear, which affects the early diagnosis, treatment decision-making, and prognosis evaluation. More and more multimodal magnetic resonance imaging (MRI) techniques have been applied for the diagnosis of mTBI, such as functional magnetic resonance imaging (fMRI), arterial spin labeling (ASL) perfusion imaging, susceptibility-weighted imaging (SWI), and diffusion MRI (dMRI). Various imaging techniques require to be used in combination with neuroimaging examinations for patients with mTBI. The understanding of the neuropathological mechanism of mTBI has been improved based on different angles. In this review, we have summarized the application of these aforementioned multimodal MRI techniques in mTBI and evaluated its benefits and drawbacks.
轻度创伤性脑损伤（mTBI）占创伤性脑损伤（TBI）病例总数的80%以上。mTBI患者的损伤机制有多种神经病理过程。然而，mTBI潜在的神经生理机制尚不清楚，这影响了早期诊断、治疗决策和预后评估。越来越多的多模态磁共振成像（MRI）技术已应用于mTBI的诊断，如功能磁共振成像（fMRI）、动脉自旋标记（ASL）灌注成像、磁敏感加权成像（SWI）和扩散MRI（dMRI）。对于mTBI患者，各种成像技术需要与神经影像学检查结合使用。基于不同角度，对mTBI神经病理机制的认识已得到提高。在本综述中，我们总结了上述多模态MRI技术在mTBI中的应用，并评估了其优缺点。
