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[苔藓样糠疹。13例临床研究]

[Lichenoid pityriasis. Clinical study of 13 cases].

作者信息

Bravo Piris J

出版信息

Med Cutan Ibero Lat Am. 1977;5(3):189-96.

PMID:357860
Abstract

13 patients with Pityriasis Lichenoides are studied clinical and histologically, showing a clinical polymorphism of the lesions, mainly in the papulous, vesiculous, and necrotic ones. The data about age, sex, evolution and response to the treatment in the present study are similar to those found by other authors. Constantly, we found, a variable degree of vasculitis. In almost all the cases there was a damage of the epithelium --exoserosis and exocytosis--, as well as presence in some cases, of red cells extravasated within the epidermis. In upper dermis we found in all biopsies, divers degrees of perivascular cell infiltration mainly composed of lymphocytes and histiocytes with predominance of the last ones, in five cases. In the majority of our cases, there was a strong relationship between the clinical and the histological aspects, but in some cases, mild lesions showed an acute microscopical picture. We are of the opinion that Pityriasis Lichenoides must be considered as a different entity from Parapsoriasis. In addition, we think that PL, is a clinical picture that manifests itself as a chronic or an acute form, and both types can be seen in the disease evolution. Finally, we could not find an evident influence and a positive response to the treatment in our patients with the classical therapeutics.

摘要

对13例点滴状副银屑病患者进行了临床和组织学研究,结果显示皮损具有临床多态性,主要表现为丘疹型、水疱型和坏死型。本研究中关于年龄、性别、病情演变及对治疗反应的数据与其他作者的研究结果相似。我们经常发现不同程度的血管炎。几乎在所有病例中均存在上皮损害——表皮松解和细胞外渗——,部分病例中还可见表皮内红细胞外渗。在所有活检标本的真皮上层,均发现不同程度的血管周围细胞浸润,主要由淋巴细胞和组织细胞组成,其中5例以组织细胞为主。在我们的大多数病例中,临床和组织学表现之间存在密切关系,但在某些病例中,轻度皮损却呈现出急性显微镜下表现。我们认为点滴状副银屑病应被视为一种与类银屑病不同的疾病实体。此外,我们认为点滴状副银屑病是一种可表现为慢性或急性形式的临床病症,在疾病演变过程中两种类型均可出现。最后,我们发现经典治疗方法对我们的患者并无明显疗效和积极反应。

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