Hood A F, Mark E J
Arch Dermatol. 1982 Jul;118(7):478-82.
To assess the specificity of the histopathologic features in the diagnosis of pityriasis lichenoides et varioliformis acuta (PLEVA), we reviewed the clinical manifestations and courses of 42 patients for whom this diagnosis was suggested in the pathology report. The histologic diagnosis of PLEVA was clinically substantiated in 16 of these 42 cases. Of the 26 cases in which PLEVA was erroneously diagnosed histologically, the correct clinical diagnosis was suggested before biopsies were done in 21 instances. In the five remaining cases, both the prebiopsy clinical diagnosis and the pathologic diagnosis proved to be incorrect. Pityriasis rosea, insect bites, and eczematous dermatitis accounted for the majority of the cases that histologically mimicked PLEVA. The constellation of histologic findings described in PLEVA (presence of intraepidermal lymphocytes and erythrocytes, dermal hemorrhage, and so-called lymphocytic vasculitis) is not specific and may be seen in a variety of dermatologic disorders.
为评估急性痘疮样苔藓样糠疹（PLEVA）组织病理学特征在诊断中的特异性，我们回顾了42例病理报告提示该诊断患者的临床表现及病程。这42例中，有16例PLEVA的组织学诊断得到临床证实。在组织学误诊为PLEVA的26例中，21例在活检前就已得出正确的临床诊断。在其余5例中，活检前临床诊断和病理诊断均不正确。玫瑰糠疹、昆虫叮咬及湿疹性皮炎占组织学上酷似PLEVA病例的大多数。PLEVA中所描述的组织学表现组合（表皮内淋巴细胞和红细胞的存在、真皮出血及所谓的淋巴细胞性血管炎）并非特异性的，可在多种皮肤病中见到。
