Department of Gastroenterology, Hepatology and Nutrition, Digestive Diseases and Surgery Institute, Cleveland Clinic, Cleveland, OH, USA.
Ann Med. 2022 Dec;54(1):1776-1786. doi: 10.1080/07853890.2022.2090601.
Pancreatitis is the leading gastrointestinal cause of hospitalizations. There are multiple short- and long-term complications associated with pancreatitis. Post-pancreatitis diabetes mellitus (PPDM) is one of the less explored complications of pancreatitis. Nonetheless, it has attracted considerable attention during the last decade. PPDM is now the second most common cause of new-onset diabetes mellitus (DM) in adults after type II DM surpassing type 1 DM. However, there exists a knowledge gap amongst practitioners regarding diagnosis, complications, and management of PPDM. In this narrative, we aim to provide a brief review regarding risks, diagnosis and management of PPDM with a special focus on dietary and lifestyle management strategies.KEY MESSAGESPost-pancreatitis diabetes mellitus (PPDM) is now the second most common cause of new-onset diabetes mellitus (DM) in adults after type II DM surpassing type 1 DM.New-onset diabetes in patients with pancreatitis could also be an early marker of occult pancreatic malignancy.Management of PPDM is complex and requires a team-based approach including gastroenterologists, endocrinologists, primary care physicians, nutritionists, and behavioural health specialists.
胰腺炎是导致住院的主要胃肠道疾病。胰腺炎有多种短期和长期并发症。胰腺炎后糖尿病(PPDM)是胰腺炎较少被探索的并发症之一。尽管如此,在过去十年中,它引起了相当多的关注。PPDM 现在是成年人中新发糖尿病(DM)的第二大常见原因,仅次于 2 型 DM,超过 1 型 DM。然而,在实践中,医生对于 PPDM 的诊断、并发症和管理仍存在知识空白。在这篇叙述性文章中,我们旨在简要回顾 PPDM 的风险、诊断和管理,特别关注饮食和生活方式管理策略。
胰腺炎后糖尿病(PPDM)现在是成年人中新发糖尿病(DM)的第二大常见原因,仅次于 2 型 DM,超过 1 型 DM。
胰腺炎患者新发糖尿病也可能是隐匿性胰腺癌的早期标志物。
PPDM 的管理很复杂,需要多学科团队的方法,包括胃肠病学家、内分泌学家、初级保健医生、营养师和行为健康专家。