Mvogo S R Ebana, Dohvoma V A, Tsimi C Mvilongo, Ndongo J A De Jésus, Mbia D A Zobo, Komatchou D Sina, Nyasse P, Epee E, Mvogo C Ebana
Faculté de médecine et des sciences biomédicales, université de Yaoundé I, Yaoundé, Cameroun; Service d'ophtalmologie-ORL-odontostomatologie, hôpital gynéco-obstétrique pédiatrique de Douala, Douala, Cameroun.
Faculté de médecine et des sciences biomédicales, université de Yaoundé I, Yaoundé, Cameroun; Service d'ophtalmologie, hôpital central de Yaoundé, Yaoundé, Cameroun.
J Fr Ophtalmol. 2022 Oct;45(8):903-907. doi: 10.1016/j.jfo.2022.03.012. Epub 2022 Jul 2.
To evaluate lacrimal secretion in patients with tropical endemic limboconjunctivitis (TELC).
We carried out a case-control study at Douala Gynaeco-Obstetric and Paediatric Hospital and in Yaoundé Central Hospital from June 10th, 2016 to September 10th, 2019. We selected patients with TELC for the first group and patients followed for ametropia as the second. In the case group, we studied the duration of symptoms and the type of TELC. For both groups, the tear film break-up time (BUT) was considered abnormal if less than 10sec. Lacrimal secretion was measured with Schirmer 1 test. Hyposecretion was defined as a Schirmer 1 test result≤10mm.
Forty patients and 40 controls were involved in the study, and 80 eyes were examined for each group. The mean age was 8.8±3.7 years. The mean duration of symptoms was 14.2±13.1 months. The mixed and palpebral forms were the most common, at 47% and 28%, respectively. We noted an unstable tear film in 48 eyes of cases and 8 eyes of controls (P<0.01). Lacrimal hyposecretion was founded in 41 eyes of cases compared to 8 eyes of the control group (P<0.01). A high risk of lacrimal hyposecretion was associated with TELC (OR=3.1; P<0.01).
Tropical endemic limboconjunctivitis increases the risk of lacrimal hyposecretion.
评估热带地方性睑缘结膜炎（TELC）患者的泪液分泌情况。
2016年6月10日至2019年9月10日，我们在杜阿拉妇产科与儿科医院以及雅温得中心医院开展了一项病例对照研究。我们选取了第一组患有TELC的患者和第二组因屈光不正接受随访的患者。在病例组中，我们研究了症状持续时间和TELC的类型。对于两组患者，如果泪膜破裂时间（BUT）少于10秒，则认为异常。使用泪液分泌试验1（Schirmer 1试验）测量泪液分泌。分泌不足定义为Schirmer 1试验结果≤10毫米。
40例患者和40例对照参与了研究，每组检查80只眼。平均年龄为8.8±3.7岁。症状的平均持续时间为14.2±13.1个月。混合性和睑缘型最为常见，分别占47%和28%。我们注意到病例组48只眼和对照组8只眼泪膜不稳定（P<0.01）。病例组41只眼出现泪液分泌不足，而对照组为8只眼（P<0.01）。泪液分泌不足的高风险与TELC相关（比值比=3.1；P<0.01）。
热带地方性睑缘结膜炎增加了泪液分泌不足的风险。
