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新型腔室模型中空气可透过型等离子体过滤器对区域消毒效果的评估。

Evaluation of zone disinfection by air-passable plasma filter in a novel chamber model.

机构信息

Department of Nano-Bio Convergence, Korea Institute of Materials Science, Changwon, Republic of Korea.

Clinical Research Centre, Masan National Tuberculosis Hospital, Changwon, Republic of Korea.

出版信息

J Hosp Infect. 2022 Oct;128:1-7. doi: 10.1016/j.jhin.2022.06.013. Epub 2022 Jul 1.

DOI:10.1016/j.jhin.2022.06.013
PMID:35788014
Abstract

BACKGROUND

Disinfection of shared spaces has become essential to minimize the spread of various diseases. An efficient disinfection device that can simultaneously inactivate airborne bacteria and surface-adhered bacteria in an enclosed space is required.

AIM

An air-passable plasma filter (APF) was developed and applied to a chamber model to evaluate the efficacy of zone disinfection.

METHODS

The 60 L chamber consisted of a nebulizer, circulation fans, temperature and humidity monitors, an air-sampling port with a sealed gate, airborne bacteria-trapping media, and a built-in fan for evaluation. After spraying each bacterial strain (Escherichia coli, Staphylococcus epidermidis, and Mycobacterium smegmatis) as a bioaerosol, airborne and surface-attached bacteria were quantified simultaneously to evaluate the zone-disinfection effect of APF.

FINDINGS

The operation of APF in the 60 L chamber showed a complete zone-disinfection effect for E. coli (10 min), S. epidermidis (10 min), and M. smegmatis (60 min) present in the air and on the walls at various locations. The time required to completely disinfect each of the airborne bacteria and surface-attached bacteria within the same space was different.

CONCLUSION

APF has the potential to exhibit significant germicidal effects on various micro-organisms and can be an effective alternative for disinfection of enclosed spaces.

摘要

背景

为了最大限度地减少各种疾病的传播,对共享空间进行消毒已变得至关重要。需要一种能够同时灭活封闭空间内空气中细菌和表面附着细菌的高效消毒设备。

目的

开发了一种可空气穿透的等离子体过滤器(APF),并将其应用于腔室模型,以评估区域消毒的效果。

方法

60L 腔室由喷雾器、循环风扇、温度和湿度监测器、带有密封门的空气取样端口、空气中细菌捕获介质以及内置风扇组成,用于评估。在将每种细菌菌株(大肠杆菌、表皮葡萄球菌和耻垢分枝杆菌)喷雾作为生物气溶胶后,同时定量空气中和表面附着的细菌,以评估 APF 的区域消毒效果。

结果

APF 在 60L 腔室中的运行显示出对空气中和墙壁上不同位置的各种细菌(大肠杆菌 10 分钟,表皮葡萄球菌 10 分钟,耻垢分枝杆菌 60 分钟)的完全区域消毒效果。完全消毒同一空间内每种空气传播细菌和表面附着细菌所需的时间不同。

结论

APF 有可能对各种微生物表现出显著的杀菌作用,并且可以成为封闭空间消毒的有效替代方法。

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