Feretis C B, Vyssoulis G P, Nikou G G, Papoutsis G G, Maidas D C, Apostolidis N S, Toutouzas P C, Philippakis M G
Am Surg. 1987 Jun;53(6):333-6.
Digoxin levels were measured perspectively in the serum of 12 patients subjected to cholecystectomy and in serum and bile (Kehr) of 15 patients who underwent cholecystectomy plus choledochostomy in order to assess adequate digitalization. All patients were volunteers with no cardiac problems. In the cholecystectomy group serum digoxin levels increased in all patients from the second to the fourth postoperative day (P = 0.0001), while in patients with choledochostomy both serum and bile digoxin levels displayed wide variations. This last finding was associated with signs reflecting inadequate digitalization, probably due to significant digoxin losses through the choledochostomy.
前瞻性地测定了12例行胆囊切除术患者血清中的地高辛水平，以及15例行胆囊切除术加胆总管造口术患者血清和胆汁（凯尔液）中的地高辛水平，以评估地高辛的充分洋地黄化情况。所有患者均为无心脏问题的志愿者。在胆囊切除术组中，所有患者的血清地高辛水平从术后第二天到第四天均升高（P = 0.0001），而在胆总管造口术患者中，血清和胆汁中的地高辛水平均有很大差异。这一最后的发现与反映洋地黄化不足的体征相关，可能是由于通过胆总管造口术导致大量地高辛流失。
