College of Chemistry and Life Science, Provincial Key Laboratory for Structural Optimization and Application of Functional Molecules, Sichuan, Chengdu Normal University, Chengdu, 611130, China.
School of Pharmacy, Institute of Pharmacy, Medical Imaging Key Laboratory of Sichuan Province, North Sichuan Medical College, Nanchong, 637000, Sichuan, China.
Mikrochim Acta. 2022 Jul 6;189(8):272. doi: 10.1007/s00604-022-05377-4.
Carbon dot decorated silver metal-organic frameworks (CD-MOFs) were successfully synthesized at room temperature by adding CDs during the formation of Ag-MOFs. The CD-MOFs have excellent optical property, stability, and good fluorescence intensity in water compared with other solvents. The fluorescence intensity of CD-MOFs was relatively stable in the range of pH 5-9. It was used to construct a sensitive and reliable fluorescent sensor for the determination of chloramphenicol (CAP). When the CAP was introduced into the CD-MOFs, the fluorescence at 427 nm was quenched at the excitation wavelength of 332 nm. Wide linear relationships were established for CAP with a limit of detection of 44 nM. The fluorescent sensor has been applied to determine CAP in milk powder sample with satisfied recoveries (104 to 109%) and good precision (< 4%). The photoinduced electron-transfer is the most important mechanism contributing to the fluorescence quenching. The synthesized CD-MOFs provide a new orientation for fluorescence determination of chloramphenicol in real samples.
碳点修饰的银金属有机骨架（CD-MOFs）通过在 Ag-MOFs 形成过程中添加 CDs 成功地在室温下合成。与其他溶剂相比，CD-MOFs 在水中具有出色的光学性能、稳定性和良好的荧光强度。CD-MOFs 的荧光强度在 pH 值 5-9 的范围内相对稳定。它被用于构建一种灵敏可靠的荧光传感器，用于测定氯霉素（CAP）。当 CAP 被引入到 CD-MOFs 中时，在 332nm 的激发波长下，427nm 处的荧光被猝灭。建立了 CAP 的宽线性关系，检测限为 44 nM。该荧光传感器已应用于测定奶粉样品中的 CAP，回收率令人满意（104%至 109%），精密度良好（<4%）。光诱导电子转移是导致荧光猝灭的最重要机制。合成的 CD-MOFs 为实际样品中氯霉素的荧光测定提供了新的方向。
