Chambers H F, Morris D L, Täuber M G, Modin G
Ann Intern Med. 1987 Jun;106(6):833-6. doi: 10.7326/0003-4819-106-6-833.
Endocarditis is a relatively frequent infection in intravenous drug users. We compared features in the cases of 102 patients with those in intravenous drug users with other causes of fever to identify risk factors predictive of endocarditis. Logistic regression analysis showed cocaine use to be strongly associated with endocarditis. This special risk involving cocaine use has not been reported previously; the explanation for it may provide insight into the pathogenesis of endocarditis.
心内膜炎在静脉注射毒品者中是一种相对常见的感染。我们将102例患者的特征与因其他发热原因而静脉注射毒品的患者进行了比较，以确定心内膜炎的预测危险因素。逻辑回归分析表明，使用可卡因与心内膜炎密切相关。这种涉及使用可卡因的特殊风险以前尚未有报道；对此的解释可能有助于深入了解心内膜炎的发病机制。
