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具有常见蛋白尿病因犬的预后因素。

Prognostic factors in dogs with common causes of proteinuria.

机构信息

Clinic for Small Animal Internal Medicine, Vetsuisse Faculty, University of Zurich.

出版信息

Schweiz Arch Tierheilkd. 2022 Jul;164(7):525-533. doi: 10.17236/sat00362.

Abstract

Little is known about the prognostic value of increased urine protein to creatinine ratios (UPC) comparing different underlying diseases in dogs. Therefore, between 2014 and 2015, dogs with a UPC of 2,0 or higher measured were retrospectively analysed at least once. They were divided into groups of the most common underlying diseases, namely primary glomerulopathy, Cushing's disease, leishmaniasis and in a group of different diseases. Possible prognostic factors, like UPC at time of diagnosis, creatinine, urine specific gravity, albumin and haematocrit, were assessed. Eighty-nine dogs with severe proteinuria were included in the study. Median time of survival was 42 days. UPC and time of survival did not differ significantly between the groups. Among the dogs with primary glomerulopathy, identified significant risk factors for death included increased UPC (p=0,03), increased creatinine (p.

摘要

关于不同基础疾病犬的尿蛋白与肌酐比值(UPC)升高的预后价值知之甚少。因此,在 2014 年至 2015 年期间,对至少测量过一次 UPC 为 2.0 或更高的犬进行了回顾性分析。它们被分为最常见的基础疾病组,即原发性肾小球疾病、库欣病、利什曼病和不同疾病组。评估了可能的预后因素,如诊断时的 UPC、肌酐、尿比重、白蛋白和红细胞压积。本研究纳入了 89 例严重蛋白尿犬。中位生存时间为 42 天。UPC 和生存时间在各组之间无显著差异。在原发性肾小球疾病犬中,死亡的显著危险因素包括 UPC 升高(p=0.03)和肌酐升高(p.

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