Birkmayer J G, Birkmayer W
Ann Clin Lab Sci. 1987 Jan-Feb;17(1):32-5.
Akinetic crises are one of the problems arising in patients with Parkinson's disease in particular after long term treatment with levo-dihydroxyphenylalanine (L-DOPA). They are characterized by severe disability to move. Increasing dosages of L-DOPA and decarboxylase or monoaminooxidase inhibitors do not improve these symptoms. Intravenously applied iron in the form of a ferri-ferro-complex exhibits a considerable benefit for all patients treated so far. They regained a remarkable mobility. Their disability score dropped from up to 90 percent down to 30 percent. The effect is dosage-dependent, and withdrawal of iron will lead again to akinetic crises.
运动不能性危象是帕金森病患者尤其是长期使用左旋多巴（L-DOPA）治疗后出现的问题之一。其特征是严重的运动障碍。增加L-DOPA及脱羧酶或单胺氧化酶抑制剂的剂量并不能改善这些症状。以铁-亚铁络合物形式静脉注射铁剂对迄今为止所有接受治疗的患者都显示出显著疗效。他们恢复了显著的活动能力。其残疾评分从高达90%降至30%。这种效果具有剂量依赖性，停用铁剂会再次导致运动不能性危象。
