Neonatology, Fukuoka Children's Hospital, Fukuoka, Fukuoka, Japan
PGDip in Neonatal Medicine, Cardiff University, Cardiff, UK.
BMJ Case Rep. 2022 Jul 6;15(7):e249174. doi: 10.1136/bcr-2022-249174.
Pericatheter thrombus calcification is a complication that arises due to central venous catheter insertion and is particularly rare in peripherally inserted central catheters (PICCs). In this case report, we reviewed the clinical course of two neonates experiencing thrombus calcification. The first case involved a male neonate weighing 445 g. His PICC dwelt in the superior vena cava for over 49 days. Although a radiograph after removal did not show any silhouette, subsequent radiographs and CT depicted a catheter-like outline. Percutaneous intravascular retrieval was performed to salvage the object. Pathological examination revealed it to be a calcified cast. The calcified thrombosis was successfully dissolved with 6 months of warfarin therapy. The second case involved a male neonate weighing 534 g. After PICC removal, a catheter-like structure was shown on ultrasonograms. It was determined that invasive procedures were unnecessary for diagnosing the calcified thrombosis based on experience with the first case.
经皮导管内血栓钙化是一种由于中心静脉导管插入而引起的并发症，在经外周插入的中心导管（PICC）中尤为罕见。在本病例报告中，我们回顾了两名发生血栓钙化的新生儿的临床经过。第一例是一名 445 克重的男性新生儿。他的 PICC 留置在腔静脉超过 49 天。尽管取出后的 X 光片未显示任何轮廓，但随后的 X 光片和 CT 显示了导管样的轮廓。通过经皮血管内取出术来抢救该物体。病理检查显示为钙化铸型。经过 6 个月的华法林治疗，钙化血栓成功溶解。第二例是一名 534 克重的男性新生儿。PICC 取出后，超声显示导管样结构。根据第一例的经验，确定无需进行侵入性操作即可诊断钙化血栓。
