Department of Gynecology, Gifu Prefectural General Medical Center, Gifu, Japan.
J Obstet Gynaecol Res. 2022 Aug;48(8):2224-2230. doi: 10.1111/jog.15242. Epub 2022 Jul 6.
Leiomyosarcoma arising from the ovarian vein has rarely been reported. Herein, we report two cases from a single institute. Given their direct connections to ovarian vessels, both leiomyosarcomas were initially suspected to be gynecological malignancies. In one case, leiomyosarcoma was discovered incidentally without any clinical symptoms; it had a close connection with the ovarian vein, was removed surgically, and the patient has survived for over 12 years. In another case, bowel obstruction caused by the tumor helped to identify metastatic leiomyosarcoma. Blood flow was supplied by the ovarian artery and grew into the lumen of the ovarian vein without invading adjacent organs. After surgical resection, the patient underwent 18 months of chemotherapy prior to palliative care. We propose that leiomyosarcoma arising from the ovarian vein should be treated as a gynecologic malignancy, especially if it develops in the lower abdomen.
由卵巢静脉起源的平滑肌肉瘤很少见。本文报道了来自同一机构的两例病例。由于它们与卵巢血管直接相连，最初都怀疑为妇科恶性肿瘤。其中一例平滑肌肉瘤无症状偶然发现，与卵巢静脉关系密切，手术切除后患者已存活 12 年以上。另一例患者因肿瘤引起肠梗阻，诊断为转移性平滑肌肉瘤。肿瘤血供来自卵巢动脉，向卵巢静脉腔内生长，未侵犯周围器官。手术切除后，患者接受了 18 个月的化疗，随后接受姑息治疗。我们认为，起源于卵巢静脉的平滑肌肉瘤应视为妇科恶性肿瘤，尤其是在下腹部发生时。
