Hong Zhen, Zheng Mingming, Li Yan, Li Shaoquan, Liu Qingran, Xie Songwang, Wang Junyong, Wang Jian, Liu Yongchang
Department of Neurovascular Intervention, Cangzhou Central Hospital, Cangzhou, Hebei, China.
Evid Based Complement Alternat Med. 2022 Jun 27;2022:1127159. doi: 10.1155/2022/1127159. eCollection 2022.
To explore the effect of acute thrombolytic therapy combined with the green channel on the thrombolytic time and neurological function in acute stroke patients.
A total of 100 acute stroke patients admitted to our hospital from August 2016 to August 2019 were recruited as the research cohort. In experimental group, 50 patients were administered green channel combined with acute thrombolytic therapy, while the patients in control group were administered general therapy. The thrombolytic times, the muscle strength grades, the FMA scores, the Barthel index levels, the NIHSS and SSS scores, the SAS and SDS scores, the arterial pressure and heart rates, the total effective rates, the incidences of postoperative adverse reactions, and the satisfaction levels were compared between the two groups.
The thrombolysis times in experimental group were shorter than those in control group. In experimental group, there were more patients with muscle strength grades 4 and 5 ( < 0.05), the FMA and Barthel index levels were higher, the NIHSS and SSS ( < 0.05) and the SAS and SDS scores were lower, the arterial pressure and heart rates were lower ( < 0.05), the incidence of postoperative adverse reactions was lower ( < 0.05), the total efficiency was higher ( < 0.05), and the satisfaction level was higher ( < 0.05).
Acute thrombolytic therapy combined with the green channel can significantly reduce the thrombolytic time and improve the neurological function in acute stroke patients.
探讨急性溶栓治疗联合绿色通道对急性脑卒中患者溶栓时间及神经功能的影响。
选取2016年8月至2019年8月我院收治的100例急性脑卒中患者作为研究队列。实验组50例患者采用绿色通道联合急性溶栓治疗,对照组患者采用常规治疗。比较两组患者的溶栓时间、肌力分级、FMA评分、Barthel指数水平、NIHSS和SSS评分、SAS和SDS评分、动脉压和心率、总有效率、术后不良反应发生率及满意度。
实验组溶栓时间短于对照组。实验组肌力4级和5级患者更多(<0.05),FMA和Barthel指数水平更高,NIHSS和SSS评分更低(<0.05),SAS和SDS评分更低,动脉压和心率更低(<0.05),术后不良反应发生率更低(<0.05),总有效率更高(<0.05),满意度更高(<0.05)。
急性溶栓治疗联合绿色通道可显著缩短急性脑卒中患者的溶栓时间,改善神经功能。