Lingas Elvina C
Internal Medicine, Presbyterian Hospital, Albuquerque, USA.
Cureus. 2022 Jun 2;14(6):e25596. doi: 10.7759/cureus.25596. eCollection 2022 Jun.
Coronavirus disease 2019 (COVID-19) is a febrile respiratory illness caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). It may develop into respiratory failure or pneumonia. Antimicrobials have facilitated medical progress for decades. However, antimicrobial resistance (AMR) limits our ability to treat diseases and undermines efforts to attain health-related sustainable development and universal health coverage objectives. Antimicrobial resistance is a major concern that must be addressed immediately. The principles of appropriate prescription, optimal use of antimicrobials, quality diagnosis and treatment, and infection reduction and prevention have led to antimicrobial stewardship initiatives. During the current COVID-19 epidemic, there are possible hazards to antimicrobial stewardship measures and drug resistance. Many people with mild illnesses but without pneumonia or moderate infections with pneumonia are administered antibiotics. Antimicrobial therapy has no documented benefit in COVID-19 patients without microbial co-infection. COVID-19 patients may have an increased risk of developing concomitant microbial infections, which would necessitate antibiotic treatment. This review evaluated the role of empiric antibiotics in COVID-19 patients.
2019冠状病毒病(COVID-19)是一种由严重急性呼吸综合征冠状病毒2(SARS-CoV-2)引起的发热性呼吸道疾病。它可能发展为呼吸衰竭或肺炎。几十年来,抗菌药物推动了医学进步。然而,抗菌药物耐药性(AMR)限制了我们治疗疾病的能力,破坏了实现与健康相关的可持续发展和全民健康覆盖目标的努力。抗菌药物耐药性是一个必须立即解决的主要问题。适当处方、抗菌药物的优化使用、高质量诊断和治疗以及感染减少与预防等原则催生了抗菌药物管理倡议。在当前的COVID-19疫情期间,抗菌药物管理措施和耐药性存在潜在风险。许多轻症但无肺炎或中度肺炎感染的患者接受了抗生素治疗。在没有微生物合并感染的COVID-19患者中,抗菌治疗并无已记录的益处。COVID-19患者发生合并微生物感染的风险可能增加,这将需要进行抗生素治疗。本综述评估了经验性抗生素在COVID-19患者中的作用。