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Switching from IL23 inhibitors to IL17 inhibitors: A safe and effective practice?

作者信息

Mastorino Luca, Roccuzzo Gabriele, Dapavo Paolo, Siliquini Niccolò, Avallone Gianluca, Rubatto Marco, Quaglino Pietro, Ribero Simone

机构信息

Department of Medical Sciences, Dermatologic Clinic, University of Turin, Turin, Italy.

出版信息

Dermatol Ther. 2022 Sep;35(9):e15697. doi: 10.1111/dth.15697. Epub 2022 Jul 19.

DOI:10.1111/dth.15697
PMID:35796147
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9540258/
Abstract
摘要

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Patients with psoriasis resistant to multiple biological therapies: characteristics and definition of a difficult-to-treat population.对多种生物疗法耐药的银屑病患者：难治性人群的特征与定义
Br J Dermatol. 2022 Aug;187(2):263-265. doi: 10.1111/bjd.21048. Epub 2022 May 24.
2
Efficacy, safety, and drug survival of IL-23, IL-17, and TNF-alpha inhibitors for psoriasis treatment: a retrospective study.IL-23、IL-17 和 TNF-α 抑制剂治疗银屑病的疗效、安全性和药物生存情况：一项回顾性研究。
J Dermatolog Treat. 2022 Jun;33(4):2352-2357. doi: 10.1080/09546634.2021.1961998. Epub 2021 Aug 13.
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A head-to-head comparison of ixekizumab vs. guselkumab in patients with moderate-to-severe plaque psoriasis: 12-week efficacy, safety and speed of response from a randomized, double-blinded trial.中度至重度斑块状银屑病患者中，ixekizumab与guselkumab的头对头比较：一项随机双盲试验的12周疗效、安全性及反应速度
Br J Dermatol. 2020 Jun;182(6):1348-1358. doi: 10.1111/bjd.18851. Epub 2020 Jan 15.
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Switching from Secukinumab to Ustekinumab in Psoriasis Patients: Results from a Multicenter Experience.从司库奇尤单抗转换为乌司奴单抗治疗银屑病患者：一项多中心经验的结果。
Dermatology. 2019;235(3):213-218. doi: 10.1159/000497274. Epub 2019 Mar 29.
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When IL-17 inhibitors fail: Real-life evidence to switch from secukinumab to adalimumab or ustekinumab.当白细胞介素 17 抑制剂失效时：从司库奇尤单抗转换为阿达木单抗或乌司奴单抗的真实世界证据。
Dermatol Ther. 2019 Mar;32(2):e12793. doi: 10.1111/dth.12793. Epub 2018 Dec 21.
6
Efficacy and safety of risankizumab in moderate-to-severe plaque psoriasis (UltIMMa-1 and UltIMMa-2): results from two double-blind, randomised, placebo-controlled and ustekinumab-controlled phase 3 trials.在中重度斑块型银屑病中的疗效和安全性（UltIMMa-1 和 UltIMMa-2）：两项双盲、随机、安慰剂对照和乌司奴单抗对照的 3 期临床试验结果。
Lancet. 2018 Aug 25;392(10148):650-661. doi: 10.1016/S0140-6736(18)31713-6. Epub 2018 Aug 7.
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Tildrakizumab versus placebo or etanercept for chronic plaque psoriasis (reSURFACE 1 and reSURFACE 2): results from two randomised controlled, phase 3 trials.替西单抗与安慰剂或依那西普治疗慢性斑块型银屑病（reSURFACE 1 和 reSURFACE 2）：两项随机对照、3 期临床试验的结果。
Lancet. 2017 Jul 15;390(10091):276-288. doi: 10.1016/S0140-6736(17)31279-5. Epub 2017 Jun 6.
8
Efficacy and safety of guselkumab, an anti-interleukin-23 monoclonal antibody, compared with adalimumab for the continuous treatment of patients with moderate to severe psoriasis: Results from the phase III, double-blinded, placebo- and active comparator-controlled VOYAGE 1 trial. Guselkumab，一种抗白细胞介素-23 单克隆抗体，与阿达木单抗相比，用于中重度银屑病患者的连续治疗：来自 III 期、双盲、安慰剂和活性对照 VOYAGE 1 试验的结果。
J Am Acad Dermatol. 2017 Mar;76(3):405-417. doi: 10.1016/j.jaad.2016.11.041. Epub 2017 Jan 2.