Department of Paediatrics, University of Chieti, Chieti, Italy.
Curr Opin Pediatr. 2022 Aug 1;34(4):400-406. doi: 10.1097/MOP.0000000000001151. Epub 2022 Jul 5.
Insulin resistance (IR) is a clinical condition due to the decline in the efficiency of insulin promoting glucose uptake and utilization. The aim of this review is to provide an overview of the current knowledge on IR in children, focusing on its physiopathology, the most appropriate methods of measurement of IR, the assessment of risk factors, the effects of IR in children, and finally giving indications on screening and treatment.
IR has evolved more and more to be a global public health problem associated with several chronic metabolic diseases.
Detecting a correct measurement method and specific risk predictors, in order to reduce the incidence of IR, represents a challenging goal.
胰岛素抵抗（IR）是一种由于胰岛素促进葡萄糖摄取和利用的效率下降而导致的临床病症。本文旨在综述儿童 IR 的现有知识，重点介绍其病理生理学、IR 最适当的测量方法、危险因素评估、IR 对儿童的影响，最后给出筛查和治疗的建议。
IR 越来越成为与多种慢性代谢性疾病相关的全球性公共卫生问题。
检测正确的测量方法和特定的风险预测因子，以降低 IR 的发生率，是一个具有挑战性的目标。
