Darby J M, Yonas H, Gur D, Latchaw R E
Arch Neurol. 1987 May;44(5):551-4. doi: 10.1001/archneur.1987.00520170077027.
The absence of cerebral blood flow is a valuable adjunct confirming clinical criteria of brain death. However, current methods to confirm absent cerebral blood flow have problems that limit their clinical use. We reviewed cerebral blood flow data obtained with xenon-enhanced computed tomography in nine patients who were being evaluated for brain death. In eight patients who met clinical criteria for brain death, mean cerebral blood flow was 1.6 +/- 2.0 mL X 100 g X min. This value was within the range of error inherent in the method, and therefore represented absent flow. In a patient with persistent respiratory efforts, flow values compatible with absent flow were obtained in the supratentorial compartment, while mean flows as high as 24 mL X 100 g X min were measured in selected regions of interest in the infratentorial compartment, correlating with the clinical evidence of residual function of the brain stem. Xenon-enhanced computed tomography may be a useful test to confirm the absence of cerebral blood flow in patients being evaluated for brain death.
脑血流缺失是确认脑死亡临床标准的一项重要辅助依据。然而，目前用于确认脑血流缺失的方法存在一些问题，限制了它们在临床上的应用。我们回顾了9例正在接受脑死亡评估患者的氙增强计算机断层扫描所获得的脑血流数据。在8例符合脑死亡临床标准的患者中，平均脑血流为1.6±2.0 mL×100 g×min。该值在该方法固有的误差范围内，因此代表血流缺失。在1例有持续呼吸努力的患者中，幕上腔获得了与血流缺失相符的血流值，而在幕下腔选定的感兴趣区域测量到平均血流高达24 mL×100 g×min，这与脑干残留功能的临床证据相关。氙增强计算机断层扫描可能是一种有用的检测方法，用于确认正在接受脑死亡评估患者的脑血流缺失情况。
