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[2022年骨不连最新进展:影像学诊断、分类及治疗算法]

[Update on non-unions 2022 : Imaging diagnostics, classification and treatment algorithms].

作者信息

Grunert Michael, Hackenbroch Carsten, von Lübken Falk

机构信息

Klinik für Nuklearmedizin, Bundeswehrkrankenhaus Ulm, Ulm, Deutschland.

Klinik für Nuklearmedizin, Universitätsklinikum Ulm, Ulm, Deutschland.

出版信息

Unfallchirurgie (Heidelb). 2022 Aug;125(8):589-601. doi: 10.1007/s00113-022-01201-z. Epub 2022 Jul 7.

Abstract

BACKGROUND

Fracture healing is a complex regenerative process. An unconsolidated fracture that will not heal without further surgical intervention is called non-union. The causes are multifactorial. Diagnostic imaging is a central pillar and provides insights into the morphology and biology of the fracture as a basis for optimal surgical treatment decisions.

AIM

Knowledge of fracture healing, targeted radiological and nuclear medical diagnostics, and interdisciplinary standardized classification are of high importance for optimal treatment.

METHODS

In this article, the proven and modern diagnostic procedures are presented, an overview of the currently used scoring and classification models is given and the optimal therapeutic approach based on the extended "diamond concept" is addressed. A possible diagnostic and therapeutic approach is shown using an algorithm.

CONCLUSION

For successful treatment of pseudarthrosis, targeted radiological and nuclear medical diagnostics with old established but also newest methods, such as dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) and hybrid imaging, are necessary. An exact classification of non-unions using additional classification models makes it possible to determine and carry out the optimal surgical treatment at an early stage.

摘要

背景

骨折愈合是一个复杂的再生过程。未经进一步手术干预就无法愈合的未愈合骨折称为骨不连。其原因是多方面的。诊断成像作为核心支柱,能够洞察骨折的形态学和生物学情况,为最佳手术治疗决策提供依据。

目的

了解骨折愈合、针对性的放射学和核医学诊断以及跨学科标准化分类,对于最佳治疗至关重要。

方法

本文介绍了经过验证的现代诊断程序,概述了当前使用的评分和分类模型,并探讨了基于扩展“钻石概念”的最佳治疗方法。通过一种算法展示了一种可能的诊断和治疗方法。

结论

为成功治疗假关节,需要使用既定的以及最新的方法进行针对性的放射学和核医学诊断,如动态对比增强磁共振成像(DCE-MRI)和混合成像。使用额外的分类模型对骨不连进行准确分类,使得能够在早期确定并实施最佳手术治疗。

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