Xie Lingwen, Xu Yaodong, Chen Ling, Liu Jiahao, Li Jiahong, Ou Yongkang, Xiong Hao
Department of Otolaryngology, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, 107 West Yanjiang Road, Guangzhou, 510120, Guangdong, China.
Institute of Hearing and Speech-Language Science, Sun Yat-Sen University, Guangzhou, Guangdong, China.
Eur Arch Otorhinolaryngol. 2023 Feb;280(2):581-587. doi: 10.1007/s00405-022-07503-7. Epub 2022 Jul 7.
To identify the characteristics of tympanogram in symptomatic Eustachian tube dysfunction (SETD) patients.
One hundred and twenty-four unilateral SETD patients presenting with type A tympanograms who underwent balloon dilation of the Eustachian tube (BDET) were recruited and assigned into effective BDET group and ineffective BDET group based on treatment effect. The unaffected ear in the same patient served as normal control. Fifty-one patients with sudden sensorineural hearing loss (SSHL) and 46 patients with Meniere's disease (MD) were selected for cases of non-ETD ear fullness. Demographics, 7-item Eustachian Tube Dysfunction Questionnaire score (ETDQ-7), and tympanograms were recorded and analyzed preoperatively and postoperatively.
Of the 124 SETD patients included in the study 94 (75.8%) showed good response to BDET based on decreased ETDQ-7 scores. There were no significantly differences in the values of tympanometric peak pressure (TPP) between diseased ears and healthy ears in SETD patients, as well as in SSHL and MD patients. Instead, TPP shifts (the difference between two values of TPP obtained under a Valsalva and Toynbee maneuver) were remarkably reduced in affected ears compared with those in unaffected ears in effective BDET group at baseline. Moreover, TPP shifts in these SETD ears significantly raised and reached the levels in healthy ears postoperatively.
This study demonstrated TPP shifts are decreased in a subset of SETD patients presenting with type A tympanograms and these patients are more likely to show good response to BDET.
确定有症状的咽鼓管功能障碍（SETD）患者的鼓室图特征。
招募124例单侧SETD且鼓室图为A型的患者，这些患者接受了咽鼓管球囊扩张术（BDET），并根据治疗效果分为BDET有效组和BDET无效组。同一患者的未受影响耳作为正常对照。选择51例突发性感音神经性听力损失（SSHL）患者和46例梅尼埃病（MD）患者作为非ETD耳闷胀的病例。记录并分析术前和术后的人口统计学数据、7项咽鼓管功能障碍问卷评分（ETDQ-7）和鼓室图。
在纳入研究的124例SETD患者中，94例（75.8%）基于ETDQ-7评分降低对BDET表现出良好反应。SETD患者的患耳与健耳之间、SSHL和MD患者的患耳与健耳之间，鼓室图峰压（TPP）值均无显著差异。相反，在基线时，有效BDET组中患耳的TPP偏移（在瓦尔萨尔瓦动作和汤因比动作下获得的两个TPP值之间的差异）与未受影响耳相比明显减小。此外，这些SETD耳的TPP偏移在术后显著升高并达到健耳水平。
本研究表明，一部分呈现A型鼓室图的SETD患者的TPP偏移减小，且这些患者更有可能对BDET表现出良好反应。
