Australian and New Zealand Intensive Care Research Centre, School of Public Health and Preventive Medicine, Monash University.
Nutrition Department, Alfred Health, Melbourne, Australia.
Curr Opin Crit Care. 2022 Aug 1;28(4):395-400. doi: 10.1097/MCC.0000000000000961. Epub 2022 Jul 5.
This review describes considerations preintensive care unit (ICU), within ICU and in the post-ICU period regarding nutrition management and the current state of the literature base informing clinical care.
Within ICU, studies have focussed on the first 5-7 days of illness in mechanically ventilated patients who are heterogeneous and with minimal consideration to premorbid nutrition state. Many evidence gaps in the period within ICU remain, with the major ones being the amount of protein to provide and the impact of longer-term nutrition interventions. Personalised nutrition and nutrition in the post-ICU period are becoming key areas of focus.
Nutrition for the critically ill patient should not be viewed in isolated time periods; what happens before, during and after ICU is likely important to the overall recovery trajectory. It is critical that the impact of nutrition on clinical and functional outcomes across hospitalisation is investigated in specific groups and using interventions in ways that are biologically plausible to impact. Areas that show promise for the future of critical care nutrition include interventions delivered for a longer duration and inclusion of oral nutrition support, individualised nutrition regimes, and use of emerging bedside body composition techniques to identify patients at nutritional risk.
本文描述了 ICU 前、ICU 期间和 ICU 后与营养管理相关的注意事项,以及为指导临床护理提供信息的文献基础的现状。
在 ICU 内,研究主要集中于机械通气患者发病的最初 5-7 天,这些患者存在异质性,很少考虑到发病前的营养状态。目前 ICU 期间仍存在许多证据空白,主要涉及提供的蛋白质量以及长期营养干预的影响。个体化营养和 ICU 后营养正成为关注的重点领域。
危重症患者的营养不应仅在孤立的时间段内考虑;在 ICU 之前、期间和之后发生的情况可能对整体康复轨迹很重要。关键是要在特定人群中调查营养对临床和功能结局的影响,并采用具有生物学合理性的干预措施来影响。未来危重症营养的有希望的领域包括延长干预时间、纳入口服营养支持、个体化营养方案,以及使用新兴的床边身体成分技术来识别有营养风险的患者。