Al-Essra Hospital, Amman, Jordan.
Aroa Biosurgery Limited, Auckland, New Zealand.
Wounds. 2022 Apr;34(4):E17-E21. doi: 10.25270/wnds/2022.e17e21.
Thermal burn injuries are common, devastating medical emergencies that are challenging to manage. Timely and effective treatment is paramount to both short- and long-term patient outcomes. Currently, medical providers and health care facilities worldwide are emphasizing the need for cost-efficient and accessible treatments; such treatments are particularly vital for vulnerable populations with limited access to advanced medical resources. The use of extracellular matrix (ECM) technologies has become widespread in the management of acute and chronic wounds, including burns. Ovine forestomach matrix (OFM) is an ECM bioscaffold isolated from sheep forestomach tissue and has been shown to be effective in soft tissue reconstruction procedures.
The use of OFM in the treatment of 2 facial thermal burn injuries, including in a pediatric patient, is described. Both patients fully recovered from their facial injuries with satisfactory cosmetic outcomes.
Although OFM technology is widely used in the management of acute and chronic wounds, the authors believe this to be the first published report of its use to aid healing in burns. Ovine forestomach matrix may provide a valuable additional tool for the management of complex burns.
热烧伤是常见的、具有破坏性的医疗急症,处理起来具有挑战性。及时有效的治疗对于患者的短期和长期预后都至关重要。目前,全球的医疗服务提供者和医疗机构都在强调需要经济高效且易于获得的治疗方法;对于获得先进医疗资源有限的弱势群体来说,这种治疗方法尤为重要。细胞外基质 (ECM) 技术在急性和慢性伤口(包括烧伤)的管理中得到了广泛应用。绵羊前胃基质 (OFM) 是一种从绵羊前胃组织中分离出的 ECM 生物支架,已被证明可有效用于软组织重建手术。
介绍了 OFM 在 2 例面部热烧伤(包括 1 例儿科患者)治疗中的应用。2 名患者的面部损伤均完全恢复,美容效果满意。
尽管 OFM 技术广泛应用于急性和慢性伤口的管理,但作者认为这是首次发表的关于其在烧伤治疗中辅助愈合的报道。绵羊前胃基质可能为复杂烧伤的治疗提供一种有价值的额外工具。