Department of Ophthalmology.
Department of Pathology, New York University Langone Medical Center, New York, NY.
Ophthalmic Plast Reconstr Surg. 2022;38(4):e112-e113. doi: 10.1097/IOP.0000000000002153. Epub 2022 Mar 21.
Apocrine hidrocystomas are benign cystic tumors derived from apocrine sweat glands; they are most commonly located in the skin of the head and neck regions. Ophthalmic occurrences typically appear at the lash line and canthi of the eyelid, although rare instances have been described in the conjunctiva, caruncle, and orbit. The authors illustrate an exceptional instance of a mobile episcleral cyst in a 12-year-old girl that developed about 2 years following strabismus surgery. The cyst was located anterior to the insertion of the left medial rectus and was excised in response to the patient's complaints of irritation. Histopathology of the excised specimen displayed an empty cyst lined by a double layer of cuboidal epithelium with the inner layer exhibiting apical decapitation secretion. Confirmatory immunohistochemistry demonstrated reactivity of both layers with CK7 and the outer myoepithelial layer with D2-40. Postoperative and traumatic cysts formed after interruption of the bulbar conjunctiva are usually conjunctival cysts lined by stratified squamous nonkeratinizing epithelium.
顶泌汗腺性汗管瘤是来源于顶泌汗腺的良性囊性肿瘤;它们最常位于头颈部皮肤。眼部病变通常出现在眼睑的睫毛线和眦部,但也有罕见的结膜、穹隆和眼眶病变的报道。作者描述了一例罕见的 12 岁女孩发生于斜视手术后 2 年的移动性球结膜囊肿。该囊肿位于左眼内直肌止点的前方,由于患者有刺激症状而被切除。切除标本的组织病理学显示,一个双层立方上皮衬里的空囊,内层表现为顶端断头分泌。免疫组织化学证实内外两层均对 CK7 有反应,而外层的肌上皮层对 D2-40 有反应。球结膜中断后形成的术后和外伤性囊肿通常是由复层扁平非角化上皮衬里的结膜囊肿。