Department of Orthopaedic Surgery, Cleveland Clinic Foundation, Cleveland, Ohio.
J Knee Surg. 2023 Jul;36(9):957-964. doi: 10.1055/s-0042-1748819. Epub 2022 Jul 7.
Smoking is a modifiable risk factor for complications following total knee arthroplasty (TKA). It is unclear if the declining prevalence of tobacco use in the U.S. population is reflected in patients undergoing elective TKA. This study aims to investigate (1) the incidence of 30-day complications following TKA in smokers and (2) trends in preoperative smoking status among TKA patients. In this study, patients undergoing primary elective TKA in the United States from 2011 to 2019 were identified in the American College of Surgeons' National Surgical Quality Improvement Program (ACS-NSQIP) database. Our cohort included 406,553 cases, 8.13% of which had smoked cigarettes within 1 year of undergoing TKA. Smokers were propensity score-matched to a group of nonsmokers, with each = 32,533. The incidences of 30-day complications, readmission, and non-home discharge were compared between groups. The rate of preoperative smoking among elective primary TKA patients remained stagnant from 2011 to 2019. Smokers had higher rates of superficial surgical site infections (SSIs; 1.1 vs. 0.5%, < 0.001), deep SSI (0.3 vs. 0.2%, = 0.012), wound disruption (0.4 vs. 0.2%, < 0.001), pneumonia (0.5 vs. 0.3%, < 0.001), and 30-day readmission (3.6 vs. 2.7%, < 0.001) compared with nonsmokers. No significant trends in 30-day complications were noted between 2011 and 2019. This study supports the success of national efforts to reduce the prevalence of smoking and reports a modest effect within the TKA population. However, almost 1 in 10 patients undergoing elective TKA continues to smoke and maintains a higher risk of postoperative complications.
吸烟是全膝关节置换术(TKA)后并发症的可改变危险因素。目前尚不清楚美国人口中烟草使用量的下降是否反映在接受择期 TKA 的患者中。本研究旨在调查:(1) 吸烟者 TKA 后 30 天并发症的发生率;(2) TKA 患者术前吸烟状况的趋势。本研究在美国外科医师学院国家手术质量改进计划(ACS-NSQIP)数据库中确定了 2011 年至 2019 年期间接受初次择期 TKA 的患者。我们的队列包括 406553 例患者,其中 8.13%的患者在接受 TKA 前 1 年内吸烟。吸烟者与一组不吸烟者进行倾向评分匹配,每组匹配 32533 例。比较两组患者 30 天并发症、再入院和非家庭出院的发生率。从 2011 年到 2019 年,择期初次 TKA 患者术前吸烟率保持不变。吸烟者的浅表手术部位感染(SSI;1.1%比 0.5%, < 0.001)、深部 SSI(0.3%比 0.2%, = 0.012)、伤口裂开(0.4%比 0.2%, < 0.001)、肺炎(0.5%比 0.3%, < 0.001)和 30 天再入院率(3.6%比 2.7%, < 0.001)均高于非吸烟者。2011 年至 2019 年间,30 天并发症无明显趋势。本研究支持减少吸烟流行的国家努力取得了成功,并报告了 TKA 人群中适度的效果。然而,近 10 名接受择期 TKA 的患者中仍有 1 人吸烟,并且术后并发症的风险仍然较高。