Rheumatology Department, UNEOS Hôpitaux Privés de Metz, Metz-Vantoux, Lorraine, France.
Biological Laboratory, UNEOS Hopitaux Prives de Metz, Metz, Lorraine, France.
BMJ Case Rep. 2022 Jul 7;15(7):e249063. doi: 10.1136/bcr-2022-249063.
A woman in her 30s received a second dose, first booster, Corminaty vaccine against the SARS-CoV-2. Three days later, the patient developed unilateral sacroiliitis. A pelvic scan revealed inflammatory joint edges, bone erosion and a heterogeneous mass of 2.5 cm in the psoas muscle. Joint puncture revealed no microcrystalline deposits, but bone marrow cells, erythroblast were identified. The standard bacterial cultures and culture for mycobacteria were negative. HLA B27 was negative, and no seroconversion was identified for HIV, Epstein-Barr virus, cytomegalovirus, chlamydia or Quantiferon. Two months later, the sacroiliitis resolved.The aetiologic approach of this erosive unilateral acute sacroiliitis in a person naïve to rheumatologic pathology was negative for inflammatory or infectious sacroiliitis. Arthralgias after vaccination are expected. Arthritis is less common, and acute sacroiliitis has not yet been described. Acute sacroiliitis may be considered a reactive sacroiliitis to the anti-COVID-19 mRNA vaccine.
一位 30 多岁的女性接种了第二剂、第一剂加强针科维希德 SARS-CoV-2 疫苗。三天后，患者出现单侧骶髂关节炎。盆腔扫描显示炎性关节边缘、骨侵蚀和腰大肌内 2.5cm 的异质性肿块。关节穿刺未见微晶沉积，但发现骨髓细胞、成红细胞。标准细菌培养和分枝杆菌培养均为阴性。HLA B27 为阴性，HIV、Epstein-Barr 病毒、巨细胞病毒、衣原体或 Quantiferon 均未发生血清转换。两个月后，骶髂关节炎消退。对于一个对风湿病学病理一无所知的人来说，这种侵蚀性单侧急性骶髂关节炎的病因学方法排除了炎症性或感染性骶髂关节炎。接种疫苗后出现关节痛是预期的。关节炎较少见，急性骶髂关节炎尚未描述。急性骶髂关节炎可能被认为是对 COVID-19 mRNA 疫苗的反应性骶髂关节炎。
