Chenkai Wu, PhD, MPH, MS, Global Health Research Center,Duke Kunshan University, Academic Building 3038, No. 8 Duke Avenue, Kunshan, Jiangsu, China, 215316, Phone: (+86) 512 36657235, E-mail:
J Frailty Aging. 2022;11(3):281-285. doi: 10.14283/jfa.2022.38.
Physical resilience is an emerging concept within the context of aging and geriatric medicine, and we previously developed and validated one such indicator based on the mismatch between persons' frailty level and multimorbidity burden. We sought to develop a simplified version for classifying physical resilience. We also examined the agreement between the simplified version and the original approach and evaluated its predictive validity.
Participants were 2,457 older adults from the Health, Aging, and Body Composition Study. We constructed a simplified version for quantifying physical resilience based on the multimorbidity burden and level of frailty (score: 0-10). Participants were grouped by the number of diseases and classified into three groups-adapters, expected agers, and premature frailers-based on the mean and SD of frailty score (less than, within, or above one standard deviation of the mean).
The Cohen's kappa between the novel resilience classification and the original approach was 0.70, and the percentage of absolute agreement was 85.4%. We observed a steep increase in years of healthy and able life from premature frailers to adapters in the simplified resilience classifications.
We developed a simplified version for quantifying physical resilience in a cohort of initially well-functioning older Black and White adults. The agreement between the simplified version and the original approach is high. Adapters had a longer healthy lifespan than expected agers and premature frailers. This user-friendly indicator could help assess patients' physical resilience in clinical settings.
身体弹性(resilience)是衰老和老年医学领域的一个新兴概念，我们之前基于人与衰弱水平和多种疾病负担之间的不匹配，开发并验证了一个这样的指标。我们试图开发一种简化版的分类方法来衡量身体弹性(resilience)。我们还比较了简化版与原始方法之间的一致性，并评估了其预测有效性。
参与者是来自健康、衰老和身体成分研究的 2457 名老年人。我们根据多种疾病负担和衰弱水平(得分：0-10)构建了一个量化身体弹性(resilience)的简化版本。参与者根据衰弱得分的均值和标准差被分为疾病数量组，并根据得分(低于、在均值内或高于均值一个标准差)分为三类：适应者、预期年龄者和过早衰弱者。
新的弹性(resilience)分类与原始方法之间的 Cohen's kappa 值为 0.70，绝对一致性百分比为 85.4%。在简化的弹性(resilience)分类中，从过早衰弱者到适应者，健康和有能力生活的年限急剧增加。
我们在最初功能良好的黑人和白人老年人队列中开发了一种量化身体弹性(resilience)的简化版本。简化版与原始方法之间的一致性很高。适应者比预期年龄者和过早衰弱者有更长的健康寿命。这个易于使用的指标可以帮助在临床环境中评估患者的身体弹性(resilience)。
