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改良的用于诊断脓毒性髋关节的柯赫尔标准:它适用于膝关节吗?

The modified Kocher criteria for septic hip: Does it apply to the knee?

作者信息

Bisht Roy U, Burns Jessica D, Smith Casey L, Kang Paul, Shrader M Wade, Belthur Mohan V

机构信息

The University of Arizona College of Medicine - Phoenix, Phoenix, AZ, USA.

Mel & Enid Zuckerman College of Public Health, Phoenix, AZ, USA.

出版信息

J Child Orthop. 2022 Jun;16(3):233-237. doi: 10.1177/18632521221106383. Epub 2022 Jun 30.

Abstract

BACKGROUND

Pediatric septic arthritis is a surgical emergency and timely diagnosis prevents serious complications. To differentiate between septic hip and transient synovitis, the predictive value of four original Kocher criteria (fever, inability to bear weight, elevated serum white blood cell count, and elevated erythrocyte sedimentation rate) plus Caird's addition of elevated C-reactive protein have been studied, termed the modified Kocher criteria. These criteria have not been tested extensively on septic knee. This study tested the utility of the modified Kocher criteria in predicting septic knee while validating it for septic hip.

METHODS

A retrospective chart review was conducted of pediatric patients evaluated at a single institution for irritable hip or knee between 2009 and 2018. Patients who underwent arthrocentesis were included and the modified Kocher criteria were applied to all.

RESULTS

One hundred fifty-five patients (96 hips and 59 knees) were identified. One hundred four (67.1%) patients had septic arthritis with 44/59 (74.6%) of knees and 60/96 (62.5%) of hips. The strongest predictors for septic hip and knee were elevated C-reactive protein (odds ratio = 26.9,  < 0.0001) and refusal to bear weight (odds ratio = 14.5,  < 0.0001), respectively. For hips, 5/5 criteria produced a 100% positive predictive value for septic arthritis. For knees, the combination of inability to bear weight and elevated C-reactive protein had a positive predictive value of 89.7%.

CONCLUSION

While all five of the modified Kocher criteria are not predictive of pediatric septic knee, the combination of two specific factors (inability to bear weight and elevated C-reactive protein) is strongly predictive. This study validates previous work that the modified Kocher criteria are predictive of septic hip.

LEVEL OF EVIDENCE

level III.

摘要

背景

小儿化脓性关节炎是一种外科急症,及时诊断可预防严重并发症。为了区分化脓性髋关节和暂时性滑膜炎,人们研究了四个原始的科赫标准(发热、无法负重、血清白细胞计数升高和红细胞沉降率升高)加上卡尔德提出的C反应蛋白升高的预测价值,即改良科赫标准。这些标准尚未在化脓性膝关节上进行广泛测试。本研究测试了改良科赫标准在预测化脓性膝关节方面的效用,同时对其在化脓性髋关节方面进行验证。

方法

对2009年至2018年在单一机构接受评估的小儿髋关节或膝关节疼痛患者进行回顾性病历审查。纳入接受关节穿刺术的患者,并对所有人应用改良科赫标准。

结果

共确定了155例患者(96例髋关节和59例膝关节)。104例(67.1%)患者患有化脓性关节炎,其中膝关节44/59例(74.6%),髋关节60/96例(62.5%)。化脓性髋关节和膝关节的最强预测因素分别是C反应蛋白升高(比值比=26.9,P<0.0001)和拒绝负重(比值比=14.5,P<0.0001)。对于髋关节,5项标准中有5项对化脓性关节炎的阳性预测值为100%。对于膝关节,无法负重和C反应蛋白升高的组合阳性预测值为89.7%。

结论

虽然改良科赫标准的所有五项并不都能预测小儿化脓性膝关节,但两个特定因素(无法负重和C反应蛋白升高)的组合具有很强的预测性。本研究验证了先前的研究结果,即改良科赫标准可预测化脓性髋关节。

证据水平

三级。

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